Identification of 4-hydroxyphenylpyruvate dioxygenase inhibitors by virtual screening, molecular docking, molecular dynamic simulation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12629
Abstract: BACKGROUND 4-Hydroxyphenylpyruvate dioxygenase (HPPD) herbicides control broadleaf and gramineous weeds with better crop safety for corn, sorghum and wheat. Multiple screening models in silico have been established to obtain novel lead compounds as HPPD inhibition… read more here.
Keywords: molecular docking; screening molecular; hydroxyphenylpyruvate dioxygenase; hppd ... See more keywords
In vivo fluorescent screening for HPPD-targeted herbicide discovery.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7117
Abstract: BACKGROUND 4-Hydroxyphenylpyruvate dioxygenase (HPPD), playing a critical role in vitamin E and plastoquinone biosynthesis in plants, has been recognized as one of the most important targets for herbicide discovery for over 30 years. Structure-based rational design… read more here.
Keywords: herbicide discovery; fluorescent; hppd; hppd targeted ... See more keywords
Cobalt (II) complex as a fluorescent sensing platform for the selective and sensitive detection of triketone HPPD inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2020.124015
Abstract: 4-Hydroxyphenylpyruvatedioxygenase (HPPD) is a Fe(II)/Co(II)-dependent enzyme which has become one of the most effective herbicide targets. HPPD inhibitors have been developed as efficient herbicides for resistant weed control. Developing a method for efficient and rapid… read more here.
Keywords: detection; hppd; fluorescent; hppd inhibitors ... See more keywords
Characterization of 4-hydroxyphenylpyruvate dioxygenases, inhibition by herbicides and engineering for herbicide tolerance in crops.
Sign Up to like & getrecommendations! Published in 2019 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2019.01.006
Abstract: 4-Hydroxyphenylpyruvate dioxgenase (HPPD) enzymes from rat and from several plants contained only about a single inhibitor-binding active site per dimer which matched the content of iron in the purified Arabidopsis thaliana and Avena sativa enzymes.… read more here.
Keywords: tolerance; hydroxyphenylpyruvate; herbicide tolerance; avena ... See more keywords
Response of a Multiple-Resistant Palmer Amaranth (Amaranthus palmeri) Population to Four HPPD-Inhibiting Herbicides Applied Alone and with Atrazine
Sign Up to like & getrecommendations! Published in 2017 at "Weed Science"
DOI: 10.1017/wsc.2017.28
Abstract: Control of multiple-resistant Palmer amaranth populations in corn will rely heavily on the use of POST 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides. Therefore, field and greenhouse experiments were conducted to: (1) evaluate Palmer amaranth control with four… read more here.
Keywords: hppd; hppd inhibiting; inhibiting herbicides; population ... See more keywords
Novel Pyrazole Amides as Potential 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02123
Abstract: 4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an important target for the development of new herbicides. HPPD inhibitors can hinder photosynthesis and induce weed death with bleaching symptoms. To explore the novel skeleton of HPPD inhibitors, a series… read more here.
Keywords: pyrazole amides; hppd; novel pyrazole; hydroxyphenylpyruvate dioxygenase ... See more keywords
Basis of Atrazine and Mesotrione Synergism for Controlling Atrazine‐ and HPPD Inhibitor‐Resistant Palmer Amaranth
Sign Up to like & getrecommendations! Published in 2019 at "Agronomy Journal"
DOI: 10.2134/agronj2019.01.0037
Abstract: 3265 AbstrAct Palmer amaranth (Amaranthus palmeri S. Watson) resistant to atrazine [6-chloro-N-ethyl-N’-(1-methylethyl)1,3,5-triazine2,4-diamine] and 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides was confirmed in a seed corn (Zea mays L.) production field in Nebraska, in 2014. Neither atrazine nor… read more here.
Keywords: mesotrione; atrazine; hppd; resistant palmer ... See more keywords
On Perception and Consciousness in HPPD: A Systematic Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.675768
Abstract: Hallucinogen-persisting perception disorder (HPPD) features as a diagnostic category in the DSM-5, ICD-11, and other major classifications, but our knowledge of the phenomenology of the perceptual symptoms involved and the changes in consciousness during the… read more here.
Keywords: consciousness hppd; perception consciousness; hppd; systematic review ... See more keywords
Computer-Aided and AILDE Approaches to Design Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147822
Abstract: 4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a pivotal enzyme in tocopherol and plastoquinone synthesis and a potential target for novel herbicides. Thirty-five pyridine derivatives were selected to establish a Topomer comparative molecular field analysis (Topomer CoMFA) model… read more here.
Keywords: hppd; design; hydroxyphenylpyruvate dioxygenase; potential hppd ... See more keywords