Articles with "hprt gene" as a keyword



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Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene.

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Published in 2021 at "Radiation research"

DOI: 10.1667/rade-21-00047.1

Abstract: The hypoxanthine-phosphoribosyltransferase (HPRT) mutation assay has been widely used to investigate gene mutations induced by radiation. Here, we developed a novel method detecting deletions of multiple exons of the HPRT gene based on real-time quantitative… read more here.

Keywords: radiation; real time; hprt gene; pcr ... See more keywords

Effects of Titanium Dioxide Nanoparticles on the Hprt Gene Mutations in V79 Hamster Cells

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Published in 2020 at "Nanomaterials"

DOI: 10.3390/nano10030465

Abstract: The genotoxicity of anatase/rutile TiO2 nanoparticles (TiO2 NPs, NM105 at 3, 15 and 75 µg/cm2) was assessed with the mammalian in-vitro Hypoxanthine guanine phosphoribosyl transferase (Hprt) gene mutation test in Chinese hamster lung (V79) fibroblasts… read more here.

Keywords: tio2; tio2 nps; hamster; hprt gene ... See more keywords