LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation.
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DOI: 10.1016/j.celrep.2020.107600
Abstract: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis. In this study, we identified leucine-rich-repeat-containing… read more here.
Keywords: hematopoiesis; hematopoietic differentiation; beta signaling; hpsc hematopoiesis ... See more keywords