Engineered Peptide Modified Hydrogel Platform for propagation of Human Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.06.034
Abstract: Human pluripotent stem cells (hPSCs) have enormous potential to alleviate cell needs for regenerative medicine, however these cells require expansion in cell colonies to maintain cell-cell contact, thus limiting the scalability needed to meet the… read more here.
Keywords: medicine; stem cells; human pluripotent; pluripotent stem ... See more keywords
Reprogramming tumor stroma using an endogenous lipid lipoxin A4 to treat pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.01.072
Abstract: Pancreatic stellate cells (PSCs) are the precursors of cancer-associated fibroblasts (CAFs), which potentiate pancreatic tumor growth and progression. In this study, we investigated whether Lipoxin A4 (LXA4), an endogenous bioactive lipid, can inhibit the differentiation… read more here.
Keywords: pancreatic cancer; hpscs; cancer; treat pancreatic ... See more keywords
ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.79095
Abstract: The mechanisms of self-renewal and pluripotency maintenance of human pluripotent stem cells (hPSCs) have not been fully elucidated, especially for the role of those poorly characterized long noncoding RNAs (lncRNAs). ESRG is a lncRNA highly… read more here.
Keywords: self renewal; hpscs; renewal pluripotency;