Single‐cell transcriptomics dissects epithelial heterogeneity in HPV+ cervical adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28480
Abstract: The intra‐ and intertumoral heterogeneity of epithelial cells in human papillomavirus (HPV+) cervical adenocarcinoma (CEAD) remains largely unknown. To investigate this issue, we performed single‐cell RNA sequencing on 19 229 epithelial cells sorted from three tumor… read more here.
Keywords: heterogeneity; cervical adenocarcinoma; single cell; highly enriched ... See more keywords
HPV cervical infections and serological status in vaccinated and unvaccinated women.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.10.078
Abstract: Understanding genital infections by Human papillomaviruses (HPVs) remains a major public health issue, especially in countries where vaccine uptake is low. We investigate HPV prevalence and antibody status in 150 women (ages 18 to 25)… read more here.
Keywords: status; cervical infections; infections serological; serological status ... See more keywords
Modeling and Mathematical Analysis of the Dynamics of HPV in Cervical Epithelial Cells: Transient, Acute, Latency, and Chronic Infections
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DOI: 10.1155/2022/8650071
Abstract: The aim of this paper is to model the dynamics of the human papillomavirus (HPV) in cervical epithelial cells. We developed a mathematical model of the epithelial cellular dynamics of the stratified epithelium of three… read more here.
Keywords: dynamics hpv; transient acute; chronic infections; cervical epithelial ... See more keywords
Coinfection of torque teno virus (TTV) and human papillomavirus (HPV) in cervical samples of women living in Tehran, Iran
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Microbiology"
DOI: 10.18502/ijm.v14i2.9185
Abstract: Background and Objectives: Torque Teno virus or transfusion-transmitted virus (TTV) is a non-enveloped virus with a single strand circular DNA genome that currently is classified in the Alphatorquevirus genus and the family of Anelloviridae. Unlike… read more here.
Keywords: papillomavirus; risk; ttv; hpv cervical ... See more keywords
Subtyping of Human Papillomavirus-Positive Cervical Cancers Based on the Expression Profiles of 50 Genes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.801639
Abstract: Background Human papillomavirus-positive (HPV+) cervical cancers are highly heterogeneous in molecular and clinical features. However, the molecular classification of HPV+ cervical cancers remains insufficiently unexplored. Methods Based on the expression profiles of 50 genes having… read more here.
Keywords: cervical cancers; expression profiles; hpv cervical; based expression ... See more keywords
Lirilumab and Avelumab Enhance Anti-HPV+ Cervical Cancer Activity of Natural Killer Cells via Vav1-Dependent NF-κB Disinhibition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.747482
Abstract: Background We investigated the efficacy and mechanism of the anti-KIR immunotherapy lirilumab and anti-PD-L1 immunotherapy avelumab on natural killer (NK) cell activity against HPV+ cervical cancer. Methods NK cell-mediated lysis of autologous biopsy-derived malignant cervical… read more here.
Keywords: cervical cancer; cell; disinhibition; hpv cervical ... See more keywords
Knowledge of Human Papillomavirus and Cervical Cancer among Women Attending Gynecology Clinics in Pretoria, South Africa
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DOI: 10.3390/ijerph19074210
Abstract: Background: Cervical cancer is mainly caused by human papillomavirus (HPV). Worldwide, knowledge of HPV and cervical cancer among women is reported to be inadequate. The study aimed to assess the knowledge and awareness of HPV… read more here.
Keywords: cancer among; among women; cancer; hpv cervical ... See more keywords
Knowledge of HPV/cervical cancer and acceptability of HPV self-sampling among women living with HIV: A scoping review.
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DOI: 10.3747/co.25.3855
Abstract: Cervical cancer rates are disproportionately high among women living with the human immunodeficiency virus (wlhiv). Cervical cancer is preventable through hpv screening, regular Pap tests, and early cancer detection. Evidence indicates that hpv and cervical… read more here.
Keywords: self sampling; knowledge; cervical cancer; review ... See more keywords