Pathological variants in HPV-independent vulvar tumours
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DOI: 10.1038/s41598-024-84688-3
Abstract: Vulvar cancer is a rare gynaecological disease that can be caused by infection with human papillomavirus (HPV). The mutational frequencies and landscape for HPV-associated and HPV-independent vulvar tumor development are supposedly two distinctly different pathways… read more here.
Keywords: variants hpv; independent vulvar; hpv independent; hpv associated ... See more keywords
217 A Novel Presentation of Recurrent HPV-independent Vulvar Squamous Cell Carcinoma with a New HPV-associated High-grade Squamous Intraepithelial Lesion
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqaf121.180
Abstract: An estimated 70% of vulvar invasive squamous cell carcinomas (SCC) are HPV-independent, while the remainder are HPV-associated invasive carcinomas which may have adjacent vulvar intraepithelial neoplasia. A 74-year-old patient presented with a new vulvar lesion.… read more here.
Keywords: dvin; hpv; lesion; hpv independent ... See more keywords
A Population-based Study Investigating the Incidence of Human Papillomavirus–Associated and Human Papillomavirus–Independent Cervical Adenocarcinomas
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DOI: 10.1097/pgp.0000000000001063
Abstract: Cervical adenocarcinomas are now classified as human papillomavirus (HPV)-associated and HPV-independent types with the former being more common. However, population-based studies regarding the relative incidences of the 2 types are few. This study investigates the… read more here.
Keywords: cervical adenocarcinomas; human papillomavirus; hpv associated; hpv independent ... See more keywords
PD‐L1 expression and immune stromal features in HPV‐independent cervical adenocarcinoma
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DOI: 10.1111/his.14435
Abstract: Human papilloma virus (HPV)‐independent cervical adenocarcinoma (CA) is usually diagnosed at an advanced stage, while the therapeutic options are limited. Therefore, effective treatment options are required. The programmed cell death 1 (PD‐1) inhibitor pembrolizumab has… read more here.
Keywords: hpv independent; independent cervical; cervical adenocarcinoma; expression ... See more keywords
PD-L1 expression in HPV-independent cervical adenocarcinoma and its prognostic significance.
Sign Up to like & getrecommendations! Published in 2021 at "Histopathology"
DOI: 10.1111/his.14552
Abstract: AIM In 2020 WHO Classification of Female Genital Tumors, endocervical adenocarcinomas (ECAs) are subclassified into HPV-associated (HPVA) and HPV-independent (HPVI) groups based on their distinct etiology and clinical behavior. This study aimed to investigate Programmed… read more here.
Keywords: ecas; hpv independent; expression; hpv ... See more keywords
Human papillomavirus and p53 status define three types of vulvar squamous cell carcinomas with distinct clinical, pathological, and prognostic features.
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14925
Abstract: INTRODUCTION Based on their etiological relationship with human papillomavirus (HPV), the 2020 WHO classification has divided vulvar squamous cell carcinomas (VSCC) into two distinct types, HPV-associated and HPV-independent, and HPV-independent tumours have recently been divided… read more here.
Keywords: vscc; hpv independent; p53 status; p53 ... See more keywords
Human papillomavirus-independent cervical cancer
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-003014
Abstract: Cervical cancer is the fourth most frequent cancer in women worldwide, representing nearly 8% of all female cancer deaths every year. The majority of cases of cervical cancer are caused by human papillomavirus (HPV); however,… read more here.
Keywords: cancer; cervical cancer; human papillomavirus; independent cervical ... See more keywords
Clinicopathological characteristics and survival outcomes in human papillomavirus independent cervical cancer: a propensity score matched analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-003159
Abstract: Objective To investigate the clinicopathological characteristics and overall survival in high-risk human papillomavirus (HPV)-independent and HPV-associated cervical cancer. Methods Patients with cervical cancer hospitalized between September 2015 and December 2019 from the Affiliated Cancer Hospital… read more here.
Keywords: cervical cancer; hpv independent; high risk; independent cervical ... See more keywords
Human papillomavirus independent status on pathologic response and outcomes in locally advanced cervical cancer managed with chemoradiotherapy followed by surgery
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2022-003940
Abstract: Objective While human papillomavirus (HPV) has been shown to play a significant role in cervical cancer carcinogenesis (HPV associated cases), a considerable percentage of cervical cancers occur independently of HPV status (HPV independent). Methods In… read more here.
Keywords: cervical cancer; hpv independent; hpv; group ... See more keywords
HPV-Independent Cervical Cancer—A New Challenge of Modern Oncology
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DOI: 10.3390/ijms262010051
Abstract: Cervical cancer is a major global health concern with serious implications for women’s health. It is most often caused by persistent infection with high-risk human papillomavirus (HPV) types. However, about 5–11% of cervical carcinoma cases… read more here.
Keywords: oncology; independent cervical; cervical cancer; hpv independent ... See more keywords