HPV E6/E7mRNA association with interleukin 10 (rs1800872) polymorphism in a group of Macedonian women
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27858
Abstract: Interleukin 10 (IL‐10) is an immunosuppressive cytokine and its genetic variants could have an indirect impact on viral biology and human papillomavirus (HPV) E6/E7 messenger RNA (mRNA) expression as well. This study evaluates the association… read more here.
Keywords: polymorphism; hpv; group; rs1800872 polymorphism ... See more keywords
Concordance of HPV load and HPV mRNA for 16 carcinogenic/possibly carcinogenic HPV types in paired smear/tissue cervical cancer specimens
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3452-8
Abstract: HPV types with high viral load are associated with cervical abnormalities. However, viral load measurements and concordance of HPV loads and viral mRNA have not been demonstrated for all high-risk/possibly high-risk (HR-/pHR-)HPV types in cervical… read more here.
Keywords: hpv mrna; hpv types; phr hpv; hpv ... See more keywords
High-Risk HPV mRNA Testing using Urine, Cervico-vaginal Self-Collected and Provider-Collected Cervical Samples among Women in Mombasa, Kenya.
Sign Up to like & getrecommendations! Published in 2022 at "Sexually transmitted diseases"
DOI: 10.1097/olq.0000000000001619
Abstract: ABSTRACT We compared HPV mRNA testing using urine, self-, and provider-collected samples for the detection of high-grade cervical cytology and assessed acceptability of urine self-collection among females who engage in sex work in Kenya. Participants… read more here.
Keywords: using urine; provider collected; mrna; hpv mrna ... See more keywords
The application of PAX1 methylation detection and HPV E6/E7 mRNA detection in cervical cancer screening
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.14869
Abstract: We aimed to explore the application of PAX1 methylation and human papillomavirus (HPV) E6/E7 mRNA detection in cervical cancer screening and to compare the efficacy with high‐risk (HR)‐HPV detection. read more here.
Keywords: application pax1; detection; hpv mrna; pax1 methylation ... See more keywords
Impact of HPV mRNA types 16, 18, 45 detection on the risk of CIN3+ in young women with normal cervical cytology
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0275858
Abstract: Background Despite a well-established cervical cancer (CC) screening program in Norway, the incidence of CC in young women is increasing, peaking at 35 years of age. 25 percent of all women diagnosed with CC had… read more here.
Keywords: normal cytology; mrna test; hpv mrna; cytology ... See more keywords
Performance of Aptima HPV E6/E7 mRNA Test for Detection of Cervical Lesions in a Large Chinese Population
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v51i11.11172
Abstract: Background: We aimed to examine the effectiveness of Aptima HPV E6/E7 mRNA test for detection of cervical lesions in a large Chinese population. Methods: Overall, 4,350 women, who received simultaneously Aptima HPV E6/E7 mRNA test… read more here.
Keywords: aptima hpv; test; detection; mrna test ... See more keywords
Performance of the Human Papillomavirus E6/E7 mRNA Assay in the Primary Screening of Cervical Cancer: Opportunistic Screening in Fujian, China
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Women's Health"
DOI: 10.2147/ijwh.s383431
Abstract: Purpose A high-risk human papillomavirus E6/E7 mRNA (HR-HPV mRNA) assay is widely used in cervical cancer screening in China. However, it is still unclear whether stand-alone HR-HPV mRNA testing is sufficient for primary screening. The… read more here.
Keywords: cervical cancer; primary screening; hpv mrna; cytology ... See more keywords
Detection of HPV mRNA in Self-collected Vaginal Samples Among Urban Ethiopian Women
Sign Up to like & getrecommendations! Published in 2020 at "AntiCancer Research"
DOI: 10.21873/anticanres.14096
Abstract: Background/Aim: Cervical cancer is the most common cancer among women in Ethiopia. The objective was to evaluate the participation rate of a free of charge vaginal self-sample (Aptima multitest swab, Hologic) for the detection of… read more here.
Keywords: hpv mrna; hpv; detection hpv; vaginal self ... See more keywords
Evaluating HPV E6/E7 mRNA expression and genotype prevalence in cervical cytology and biopsy samples from Yunnan Province, China
Sign Up to like & getrecommendations! Published in 2025 at "ecancermedicalscience"
DOI: 10.3332/ecancer.2025.1893
Abstract: Persistent infection with high-risk human papillomavirus (HR-HPV) is a major contributor to the development of high-grade cervical lesions and invasive cervical cancer. The expression of HR-HPV E6/E7 oncoproteins is a key factor in the progression… read more here.
Keywords: invasive cervical; cytology; hpv mrna; cervical cancer ... See more keywords
Diagnostic value of HPV E6/E7 mRNA in screening for cervical intraepithelial neoplasia grade 2 or worse: A systematic review and meta‑analysis
Sign Up to like & getrecommendations! Published in 2024 at "Oncology Letters"
DOI: 10.3892/ol.2024.14364
Abstract: Histology is considered the gold standard for diagnosing the pathological progress of cervical cancer development, while cervical intraepithelial neoplasia of grade 2 or worse (CIN2+) is the cutoff for intervention in clinical practice. The diagnostic… read more here.
Keywords: mrna screening; cin2; hpv mrna; diagnostic value ... See more keywords
Clinical value of human papillomavirus E6/E7 mRNA testing in patients with atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive and Developmental Medicine"
DOI: 10.4103/2096-2924.248485
Abstract: Objective: To explore the clinical significance of the quantitative detection of human papillomavirus (HPV) E6/E7mRNA in triage of patients with atypical squamous cells of undetermined significance (ASC-US) and low-grade squamous intraepithelial lesion (LSIL). Methods: A… read more here.
Keywords: grade squamous; hpv mrna; squamous intraepithelial; hpv ... See more keywords