HPV8 activates cellular gene expression mainly through Sp1/3 binding sites.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.06.019
Abstract: The human papillomavirus type 8 (HPV8) is associated with skin cancer development. The goal of this study was to investigate the effects of HPV8 oncoproteins on cellular gene expression and the identification of key regulators.… read more here.
Keywords: hpv8; cellular gene; gene expression; sp1 binding ... See more keywords
Beta Human Papillomavirus 8 E6 Induces Micronucleus Formation and Promotes Chromothripsis
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DOI: 10.1128/jvi.01015-22
Abstract: Some beta genus human papillomaviruses (β-HPVs) may promote skin carcinogenesis by inducing mutations in the host genome. Supporting this, the E6 protein from β-HPV8 (8 E6) promotes skin cancer in mice with or without UV exposure.… read more here.
Keywords: human papillomaviruses; beta; hpv8; beta genus ... See more keywords
Human Beta Papillomavirus Type 8 E1 and E2 Proteins Suppress the Activation of the RIG-I-Like Receptor MDA5
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DOI: 10.3390/v14071361
Abstract: Persistent infections of the skin with the human papillomavirus of genus beta (β-HPV) in immunocompetent individuals are asymptomatic, but in immunosuppressed patients, β-HPV infections exhibit much higher viral loads on the skin and are associated… read more here.
Keywords: papillomavirus; beta; hpv8; expression ... See more keywords