Gefitinib Inhibits Rifampicin-Induced CYP3A4 Gene Expression in Human Hepatocytes
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DOI: 10.1021/acsomega.2c03270
Abstract: During multidrug combination chemotherapy, activation of the nuclear receptor and the transcription factor human pregnane xenobiotic receptor (hPXR) has been shown to play a role in the development of chemoresistance. Mechanistically, this could occur due… read more here.
Keywords: hpxr; expression human; gene expression; cyp3a4 gene ... See more keywords