Articles with "hras q61" as a keyword



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Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-04128-5

Abstract: Adenomyoepithelioma of the breast is a rare tumor characterized by epithelial−myoepithelial differentiation, whose genetic underpinning is largely unknown. Here we show through whole-exome and targeted massively parallel sequencing analysis that whilst estrogen receptor (ER)-positive adenomyoepitheliomas… read more here.

Keywords: mutations hras; hotspot mutations; pathway genes; hras q61 ... See more keywords