Articles with "hrd genome" as a keyword



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Recapitulating the clinical scenario of BRCA‐associated pancreatic cancer in pre‐clinical models

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Published in 2018 at "International Journal of Cancer"

DOI: 10.1002/ijc.31292

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. BRCA‐associated PDAC comprises a clinically relevant subtype. A portion of these patients are highly susceptible to DNA damaging therapeutics, however, responses are heterogeneous and… read more here.

Keywords: brca associated; hrd genome; treatment;