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Effectiveness and Safety of Niraparib as Neoadjuvant Therapy in Advanced Ovarian Cancer With Homologous Recombination Deficiency (NANT): Study Protocol for a Prospective, Multicenter, Exploratory, Phase 2, Single-Arm Study

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.852772

Abstract: Background Ovarian cancer (OC) is a heterogeneous gynecological malignancy with a poor prognosis as the majority of patients are diagnosed at an advanced stage. Neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) is recommended… read more here.

Keywords: ovarian cancer; niraparib neoadjuvant; recombination deficiency; study ... See more keywords