Time trends in prevalence of p16 positivity and combined HPV/p16 positivity in a large cohort of Danish vulvar cancer patients
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34446
Abstract: Vulvar cancer is rare, but causes substantial morbidity in affected patients. A subset of vulvar cancers is caused by high‐risk human papillomavirus (hrHPV), which primarily exerts its oncogenic effect through upregulation of tumor suppressor protein… read more here.
Keywords: hrhpv; positivity; p16 positivity; prevalence ... See more keywords
Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets.
Sign Up to like & getrecommendations! Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.06.026
Abstract: BACKGROUND Vulvar squamous cell carcinoma (VSCC) constitutes over 90% of vulvar cancer. Its pathogenesis can follow two different pathways; high risk human papillomavirus (hrHPV)-dependent and HPV-independent. Due to the rarity of VSCC, molecular mechanisms underlying… read more here.
Keywords: hrhpv hrhpv; somatic mutation; vscc; hrhpv ... See more keywords
Nationwide Prevalence and Genotype Distribution of High-Risk Human Papillomavirus Infection in China.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqab181
Abstract: OBJECTIVES Extended high-risk human papillomavirus (hrHPV) genotype testing has recently been introduced in routine cervical cancer screening. Changes in national and regional hrHPV genotype prevalence offer an objective baseline indicator of the future impact of… read more here.
Keywords: infection; genotype; prevalence; hpv hpv ... See more keywords
Screening strategies for the detection of anal high-grade squamous intraepithelial lesions in women living with HIV.
Sign Up to like & getrecommendations! Published in 2020 at "AIDS"
DOI: 10.1097/qad.0000000000002694
Abstract: OBJECTIVE HIV-infected women (WLHIV) have >10-fold higher risk for squamous cell cancer of the anus (SCCA). Experts suggest cytology-based strategies developed for cervical cancer screening may prevent anal cancer by detecting anal histological High-Grade Squamous… read more here.
Keywords: high grade; screening strategies; hrhpv; cytology ... See more keywords
Assessing the Cervicovaginal Microbiota in the Context of hrHPV Infections: Temporal Dynamics and Therapeutic Strategies
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01619-22
Abstract: Cervical cancer is the third leading cause of female cancers globally, resulting in more than 300,000 deaths every year. The majority of all cervical cancers are caused by persistent infections with high-risk human papillomaviruses (hrHPV)… read more here.
Keywords: hrhpv; cervicovaginal microbiota; composition; cancer ... See more keywords
P11 Immediate colposcopy findings among women with high risk HPV other than HVPV16/18 and normal cytology
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.74
Abstract: Introduction/Background Persistent infection with 1 of 14 high-risk genotypes Human Papilloma Virus (HPV) genotypes is the crucitial for the development of cervical cancer. high grade cervical cancer precursors. These HPV genotypes can be named as… read more here.
Keywords: cin; high risk; hpv hpv; hrhpv ... See more keywords
P372 Bacterial vaginosis and high-risk human papillomavirus coinfection among african american women in the united states
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2019-sti.474
Abstract: Background Bacterial vaginosis (BV) increases the risk of many sexually transmitted infections. The co-occurrence of persistent BV and high-risk HPV (HrHPV) increases the risk of developing cervical cancer. This study aims to investigate the co-occurrence… read more here.
Keywords: high risk; bacterial vaginosis; hrhpv; american women ... See more keywords
Negative Predictive Value of Human Papillomavirus Testing: Implications for Anal Cancer Screening in People Living with HIV/AIDS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Oncology"
DOI: 10.1155/2020/6352315
Abstract: Objectives People living with HIV/AIDS (PLWHA) have an increased incidence of anal squamous cell carcinoma. Since high-risk human papillomavirus (hrHPV) is the primary cause, hrHPV DNA testing may play an important role in anal cancer… read more here.
Keywords: hiv aids; living hiv; hrhpv; human papillomavirus ... See more keywords
Persistence of cervical high-risk human papillomavirus in women living with HIV in Denmark – the SHADE
Sign Up to like & getrecommendations! Published in 2019 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-019-4377-5
Abstract: BackgroundWomen living with HIV (WLWH) have high rates of persistent high-risk human papillomavirus (hrHPV) infections and cervical cancer. We aimed to assess the distribution of hrHPV genotypes, risk factors of type-specific hrHPV persistence, and high-grade… read more here.
Keywords: risk; denmark; hiv; pathology ... See more keywords
High-risk human papillomavirus status and prognosis in invasive cervical cancer: A nationwide cohort study
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DOI: 10.1371/journal.pmed.1002666
Abstract: Background High-risk human papillomavirus (hrHPV) infection is established as the major cause of invasive cervical cancer (ICC). However, whether hrHPV status in the tumor is associated with subsequent prognosis of ICC is controversial. We aim… read more here.
Keywords: status; prognosis; cervical cancer; hrhpv ... See more keywords
HPV genotyping of cervical histologic specimens of 61, 422 patients from the largest women hospital in China
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1161631
Abstract: Objectives We investigated HPV genotypes in a large cohort of patients with definitive cervical histologic diagnosis. Methods HPV testing was performed by real-time PCR assay, including 18 high-risk HPV (hrHPV) and 3 low-risk HPV (lrHPV).… read more here.
Keywords: hrhpv; cervical histologic; hpv; 422 patients ... See more keywords