Elucidation of molecular mechanism of stability of the heme-regulated eIF2α kinase upon binding of its ligand, hemin in its catalytic kinase domain
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DOI: 10.1080/07391102.2017.1368417
Abstract: The eIF2α kinase activity of the heme-regulated inhibitor (HRI) is regulated by heme which makes it a unique member of the family of eIF2α kinases. Since heme concentrations create an equilibrium for the kinase to… read more here.
Keywords: heme; kinase; eif2 kinase; stability ... See more keywords