Sequence Analysis of the Fusion Protein Gene of Human Respiratory Syncytial Virus Circulating in China from 2003 to 2014
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DOI: 10.1038/s41598-018-35894-3
Abstract: The human respiratory syncytial virus (HRSV) fusion (F) protein is important for HRSV infection, but few studies have examined the genetic diversity of the F gene from Chinese samples. In this study, a total of… read more here.
Keywords: protein; 2003 2014; hrsv; hrsv sequences ... See more keywords
From animal studies into clinical trials: the relevance of animal models to develop vaccines and therapies to reduce disease severity and prevent hRSV infection
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2022.2123468
Abstract: ABSTRACT Introduction Human respiratory syncytial virus (hRSV) is an important cause of lower respiratory tract infections in the pediatric and the geriatric population worldwide. There is a substantial economic burden resulting from hRSV disease during… read more here.
Keywords: relevance; animal models; clinical trials; disease ... See more keywords
Incidence of respiratory syncytial virus infection in children with congenital heart disease undergoing immunoprophylaxis with palivizumab in Pará state, north region of Brazil
Sign Up to like & getrecommendations! Published in 2019 at "BMC Pediatrics"
DOI: 10.1186/s12887-019-1681-6
Abstract: BackgroundPalivizumab prophylaxis for the human respiratory syncytial virus (HRSV) has been reported to reduce the risk of hospital admissions related to HRSV in children with congenital heart disease (CHD). These children are at high risk… read more here.
Keywords: immunoprophylaxis palivizumab; hrsv; respiratory syncytial; infection ... See more keywords
The significance of human respiratory syncytial virus (HRSV) in children from Ghana with acute lower respiratory tract infection: A molecular epidemiological analysis, 2006 and 2013-2014
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DOI: 10.1371/journal.pone.0203788
Abstract: Background Acute lower respiratory tract infection (ALRI) is a leading cause of childhood morbidity and mortality in developing countries. Globally, human respiratory syncytial virus (HRSV) is the most common pathogen of ALRI in infants and… read more here.
Keywords: lower respiratory; hrsv; respiratory tract; acute lower ... See more keywords
Establishment and application of a lethal model of an HRSV-long variant strain in BALB/c mice
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DOI: 10.1538/expanim.22-0042
Abstract: Human respiratory syncytial virus (HRSV) is a major cause of lower respiratory tract infection in infants. The lack of ideal animal models is one of the major obstacles in evaluateing the efficacy of HRSV vaccines.… read more here.
Keywords: balb mice; hrsv; lethal model; mice ... See more keywords
Virological surveillance of human respiratory syncytial virus A and B at a tertiary hospital in Catalonia (Spain) during five consecutive seasons (2013-2018).
Sign Up to like & getrecommendations! Published in 2019 at "Future microbiology"
DOI: 10.2217/fmb-2018-0261
Abstract: AIM Human respiratory syncytial virus (HRSV) is the main cause of respiratory tract infections among infants. MATERIALS & METHODS In the present study, the molecular epidemiology of HRSV detected from 2013 to 2017 has been… read more here.
Keywords: respiratory syncytial; hrsv; syncytial virus; respiratory ... See more keywords
Functional Impairment of Mononuclear Phagocyte System by the Human Respiratory Syncytial Virus
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DOI: 10.3389/fimmu.2017.01643
Abstract: The mononuclear phagocyte system (MPS) comprises of monocytes, macrophages (MΦ), and dendritic cells (DCs). MPS is part of the first line of immune defense against a wide range of pathogens, including viruses, such as the… read more here.
Keywords: hrsv; respiratory syncytial; mononuclear phagocyte; phagocyte system ... See more keywords
A Recombinant BCG Vaccine Is Safe and Immunogenic in Neonatal Calves and Reduces the Clinical Disease Caused by the Respiratory Syncytial Virus
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.664212
Abstract: The human respiratory syncytial virus (hRSV) constitutes a major health burden, causing millions of hospitalizations in children under five years old worldwide due to acute lower respiratory tract infections. Despite decades of research, licensed vaccines… read more here.
Keywords: hrsv; rbcg hrsv; vaccine safe; vaccine ... See more keywords
Increased Heme Oxygenase 1 Expression upon a Primary Exposure to the Respiratory Syncytial Virus and a Secondary Mycobacterium bovis Infection
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DOI: 10.3390/antiox11081453
Abstract: The human respiratory syncytial virus (hRSV) is the leading cause of severe lower respiratory tract infections in infants. Because recurrent epidemics based on reinfection occur in children and adults, hRSV has gained interest as a… read more here.
Keywords: infection; expression; mycobacterium; hrsv ... See more keywords
Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia—Implications for Vaccine Design
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DOI: 10.3390/ijms18030556
Abstract: The human respiratory syncytial virus (hRSV) is the causative agent for high rates of hospitalizations due to viral bronchiolitis and pneumonia worldwide. Such a disease is characterized by an infection of epithelial cells of the… read more here.
Keywords: respiratory syncytial; hrsv; syncytial virus; infection ... See more keywords
Changes in the Etiology of Acute Respiratory Infections among Children in Novosibirsk, Russia, between 2019 and 2022: The Impact of the SARS-CoV-2 Virus
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DOI: 10.3390/v15040934
Abstract: A wide range of human respiratory viruses are known that may cause acute respiratory infections (ARIs), such as influenza A and B viruses (HIFV), respiratory syncytial virus (HRSV), coronavirus (HCoV), parainfluenza virus (HPIV), metapneumovirus (HMPV),… read more here.
Keywords: etiology; hrsv; acute respiratory; virus ... See more keywords