Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Psychiatric Genetics"
DOI: 10.1097/ypg.0000000000000303
Abstract: Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Previous evidence shows that miR-15b-5p, hsa-let7g-5p and hsa-let7d-5p might confer potential blood biomarkers for timely diagnosis of… read more here.
Keywords: hsa; hsa let7g; alzheimer disease; mir 15b ... See more keywords
Hyperglycemia‐related FAS gene and hsa‐let‐7b‐5p as markers of poor outcomes for ischaemic stroke
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Neurology"
DOI: 10.1111/ene.14288
Abstract: Hyperglycemia in acute stroke leads to poor neurological outcomes. The role of microRNA (miRNA) in hyperglycemia‐associated genes can provide new avenues for stroke prognostic applications. We aimed to identify novel genes and their regulated miRNAs… read more here.
Keywords: related fas; fas gene; gene hsa; hyperglycemia related ... See more keywords
Expression of hsa-let-7b-5p, hsa-let-7f-5p, and hsa-miR-222-3p and their putative targets HMGA2 and CDKN1B in typical and atypical carcinoid tumors of the lung
Sign Up to like & getrecommendations! Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317728417
Abstract: Typical and atypical carcinoid tumors belong to the neuroendocrine lung tumors. They have low recurrence and proliferation rate, lymph node, and distant metastases. Nevertheless, these tumors have shown a more aggressive behavior. In the last… read more here.
Keywords: carcinoid tumors; mir 222; hsa mir; hsa let ... See more keywords
Endothelin-1 gen (EDN1) regulating miRNAs are downregulated in Idiopathic Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2020.3461
Abstract: Background: Pulmonary arterial hypertension is a disease wlith an extremely important genetic basis. Micro RNAs (miRNAs) are non-coding RNAs that range in size 17-25 nucleotides and regulate a large variety of biological functions. The aim… read more here.
Keywords: endothelin gen; gen edn1; arterial hypertension; pulmonary arterial ... See more keywords
Positive regulation of innate immune response by miRNA-let-7a-5p
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1025539
Abstract: Background: We have hypothesized that different factors are involved in the severity of ACD and AD because some but not all patients with atopic dermatitis (AD) present with allergic conjunctival disease (ACD) including severe types… read more here.
Keywords: hsa let; acd; hsa mir; innate immune ... See more keywords
Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12070829
Abstract: Tic disorders (TDs) are a series of childhood neuropsychiatric disorders characterized by involuntary motor and/or vocal tics and commonly comorbid with several other psychopathological and/or behavioral disorders (e.g., attention deficit hyperactivity disorder and obsessive–compulsive disorder),… read more here.
Keywords: tic disorders; hsa let; diagnosis; let hsa ... See more keywords
Identification of Specific microRNAs in Adipose Tissue Affected by Lipedema
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DOI: 10.3390/cimb46110710
Abstract: Lipedema is a chronic disorder affecting women with a 10% incidence worldwide. It is often confused with obesity. This study was undertaken to study microRNAs in lipedema tissue assessed by direct hybridization using the robust… read more here.
Keywords: hsa mir; hsa let; target; identification specific ... See more keywords
A Combination of Microarray-Based Profiling and Biocomputational Analysis Identified miR331-3p and hsa-let-7d-5p as Potential Biomarkers of Ulcerative Colitis Progression to Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25115699
Abstract: Ulcerative colitis (UC), an inflammatory bowel disease (IBD), may increase the risk of colorectal cancer (CRC) by activating chronic proinflammatory pathways. The goal of this study was to find serum prediction biomarkers in UC to… read more here.
Keywords: cancer; progression; hsa mir; hsa let ... See more keywords
Therapeutic Effects of Engineered Exosomes from RAW264.7 Cells Overexpressing hsa-let-7i-5p against Sepsis in Mice—A Comparative Study with Human Placenta-Derived Mesenchymal Stem Cell Exosomes
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm14060619
Abstract: This study compared the therapeutic effects of engineered exosomes derived from RAW264.7 cells overexpressing hsa-let-7i-5p (engineered exosomes) to exosomes from human placenta-derived mesenchymal stem cells (hpMSC exosomes) against sepsis-induced acute lung injury. Adult male C57BL/6… read more here.
Keywords: raw264 cells; effects engineered; therapeutic effects; engineered exosomes ... See more keywords
Serum exosomal hsa-let-7f-5p: A potential diagnostic biomarker for metastatic pancreatic cancer detection
Sign Up to like & getrecommendations! Published in 2025 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v31.i26.109500
Abstract: BACKGROUND Exosomal microRNAs (miRNAs) have emerged as promising biomarkers for cancer diagnosis due to their stability, tumor specificity, and accessibility. However, the diagnostic potential of serum exosomal miRNAs in metastatic pancreatic cancer remains underexplored. AIM… read more here.
Keywords: cancer; metastatic pancreatic; serum exosomal; hsa let ... See more keywords
Pre-miRNA Hsa-Let-7a-2: a Novel Intracellular Partner of Angiotensin II Type 2 Receptor Negatively Regulating its Signals
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.70455
Abstract: G protein-coupled receptors (GPCRs) are the largest family of druggable targets, and their biological functions depend on different ligands and intracellular interactomes. Some microRNAs (miRNAs) bind as ligands to RNA-sensitive toll-like receptor 7 to regulate… read more here.
Keywords: hsa let; let; type receptor; pre mirna ... See more keywords