Integration of bioinformatics analysis and experimental validation identifies plasma exosomal miR‐103b/877‐5p/29c‐5p as diagnostic biomarkers for early lung adenocarcinoma
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DOI: 10.1002/cam4.4788
Abstract: The aim of this study was to identify miRNAs in plasma exosomes as noninvasive biomarkers for the early diagnosis of lung adenocarcinoma (LUAD). First, exosomal miRNA profiling of three patients with early LUAD and three… read more here.
Keywords: biomarkers early; hsa mir; 103b 877; mir 103b ... See more keywords
hsa‐mir‐133a‐2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3‐mediated PI3K/ATK pathway
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DOI: 10.1002/cam4.5380
Abstract: Cervical cancer, one of the common types of malignant tumors progressed in women, is on the rise in developing countries. Numerous previous studies have demonstrated that hsa‐mir‐133a‐2 miRNA is abnormally expressed in cervical cancer cells.… read more here.
Keywords: cervical cancer; cancer; proliferation invasion; hsa mir ... See more keywords
A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression
Sign Up to like & getrecommendations! Published in 2018 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22159
Abstract: The transporter associated with antigen processing 2 (TAP2) is involved in the development of multidrug resistance and the etiology of immunological diseases. In this study, we investigated whether the expression of TAP2 can be perturbed… read more here.
Keywords: hsa mir; gene; mir 1270; snp ... See more keywords
Overexpression of Hsa‐miR‐320 Is Associated With Invasion and Metastasis of Ovarian Cancer
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DOI: 10.1002/jcb.26009
Abstract: Ovarian cancer is one of the most common malignant tumor of female genital organs which ranks the third morbidity. We aimed to provide a better understanding of the mechanism of invasion and metastasis of ovarian… read more here.
Keywords: invasion; hsa mir; metastasis; ovarian cancer ... See more keywords
Epigallocatechin‐3‐gallate inhibited cancer stem cell–like properties by targeting hsa‐mir‐485‐5p/RXRα in lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27117
Abstract: Non–small‐cell lung cancer (NSCLC) appears to be a significant threat to public health worldwide. MicroRNAs have been identified as significant regulators for the development of NSCLC. Previous reports have suggested that hsa‐mir‐485‐5p is dysregulated in… read more here.
Keywords: cancer; hsa mir; mir 485; rxr ... See more keywords
Identification of a six-microRNA signature as a potential diagnostic biomarker in breast cancer tissues.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24010
Abstract: BACKGROUND Breast cancer (BC) is by far the most common malignancy among women. Epigenetic modulators, microRNAs in particular, may set stages for BC development and its progression. Herein, we aimed to assess the diagnostic potentiality… read more here.
Keywords: breast; hsa mir; biomarker; signature ... See more keywords
Identification of hsa‐mir‐34a, hsa‐mir‐124, and hsa‐mir‐204 as signatures for cataract
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DOI: 10.1002/jcp.27741
Abstract: Cataract, one of the common age‐related diseases that remains the leading cause of blindness worldwide. There have been studies pertaining to microRNA (miRNA) effects on cataract pathogenesis. However, the results were different from each other… read more here.
Keywords: target genes; hsa mir; mir 34a; hsa ... See more keywords
Multiomics endotyping of preterm infants with bronchopulmonary dysplasia and pulmonary hypertension—A pilot study
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DOI: 10.1002/pul2.12232
Abstract: Abstract Pulmonary hypertension associated with bronchopulmonary dysplasia is a severe complication of preterm birth resulting in high mortality of up to 50% within the first 2 years of life. There is a direct relationship between… read more here.
Keywords: hsa mir; pulmonary hypertension; bronchopulmonary dysplasia; hypertension ... See more keywords
The effect of low molecular weight‐polycyclic aromatic hydrocarbons responsive hsa_circ_0039929/hsa‐miR‐15b‐3p_R‐1/FGF2 circuit on inflammatory response of A549 cells via the PI3K/AKT pathway and epithelial‐mesenchymal transition process
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DOI: 10.1002/tox.23546
Abstract: Inflammation is widely recognized as an essential inducer of epithelial‐mesenchymal transition (EMT). Meanwhile, competitive endogenous RNA (ceRNA) has been involved in a variety of disease processes. Therefore, the aim of the current study is to… read more here.
Keywords: circ 0039929; mir 15b; hsa; hsa circ ... See more keywords
Hsa_circ_0008500 inhibits apoptosis of adipose-derived stem cells under high glucose through hsa-miR-1273h-5p/ELK1 axis.
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DOI: 10.1002/tox.23801
Abstract: Preliminary researches have confirmed that the number of apoptosis of adipose tissue-derived stem cells (ADSCs) in patients with diabetes is significantly increased, leading to a difficult healing wound. Increasing researches revealed that circular RNAs (circRNAs)… read more here.
Keywords: hsa; hsa circ; hsa mir; mir 1273h ... See more keywords
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2018): Poster Abstracts
Sign Up to like & getrecommendations! Published in 2018 at "Osteoporosis International"
DOI: 10.1007/s00198-018-4465-1
Abstract: Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease that is characterized by severe tissue damage and chronic synovial inflammation. Using analysis of gene polymorphism, biochemical assays, and proteomics approaches, several promising biomarkers for treatment… read more here.
Keywords: hsa mir; disease activity; group;