Stem cells: HSC function determined by epigenetic memory
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DOI: 10.1038/nrm.2016.161
Abstract: The functional behaviour of haematopoietic stem cells is determined in a cell-autonomous manner by clone-specific epigenetic modifications. read more here.
Keywords: determined epigenetic; hsc function; cells hsc; function determined ... See more keywords
Age-related High-frequency Hearing Loss Is Not Associated With Horizontal Semicircular Canal Function
Sign Up to like & getrecommendations! Published in 2022 at "Ear and Hearing"
DOI: 10.1097/aud.0000000000001252
Abstract: Objective: Investigate the association between age-related hearing loss and reduced peripheral vestibular function using paired assessments of high-frequency hearing and horizontal semicircular canal (HSC) function. We hypothesized that age-related high-frequency hearing loss would be correlated… read more here.
Keywords: function; age related; hearing loss; age ... See more keywords
Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy.
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019003105
Abstract: Aging is associated with significant changes in the hematopoietic system, including increased inflammation, impaired hematopoietic stem cell (HSC) function, and increased incidence of myeloid malignancy. Inflammation of aging ("inflammaging") has been proposed as a driver… read more here.
Keywords: mir 146a; hsc function; inflammation; malignancy ... See more keywords