Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-114314
Abstract: The gene regulatory networks (GRN) governing maintenance and expansion of normal and leukemic human hematopoietic stem-cells (HSC and LSC) are not well understood. Typically, GRNs are inferred from gene expression (GE) data of a limited… read more here.
Keywords: hsc lsc; human hsc; gene regulatory; lsc ... See more keywords
Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2021.280404
Abstract: The immune receptor TREM1 (Triggering receptor expressed on myeloid cells 1) is a master regulator of inflammatory response. Compelling evidence suggests important pathological roles for TREM1 in various types of solid tumors. However, the role… read more here.
Keywords: hsc lsc; dna damage; pre leukemic; trem1 ... See more keywords