Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells
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DOI: 10.18632/oncotarget.16377
Abstract: The role of IL-2 in HSC maintenance is unknown. Here we show that Il2−/− mice develop severe anomalies in HSC maintenance leading to defective hematopoiesis. Whereas, lack of IL-2 signaling was detrimental for lympho- and… read more here.
Keywords: cell axis; hematopoiesis; maintenance; hsc maintenance ... See more keywords