T‐cell depleted HLA‐haploidentical HSCT in a child with neuromyelitis optica
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DOI: 10.1002/acn3.50843
Abstract: Neuromyelitis optica is an immune‐mediated disease characterized by a relapsing course, resulting in progressive disability. In children, given the long life expectancy, a disease‐modifying treatment could be particularly desirable. Unfortunately, the currently available treatment strategies… read more here.
Keywords: neuromyelitis optica; cell depleted; hla haploidentical; hsct ... See more keywords
Haploidentical vs matched unrelated donor transplantation for acute myeloid leukemia in remission: A prospective comparative study
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DOI: 10.1002/ajh.25993
Abstract: Despite comparable outcomes of haploidentical transplants (Haplo‐HSCT) with HLA‐matched unrelated transplants (MUD‐HSCT) in retrospective comparisons, few studies have prospectively compared Haplo‐HSCT with MUD‐HSCT in AML. Here, we prospectively compared the outcomes of Haplo‐HSCT with MUD‐HSCT… read more here.
Keywords: haplo hsct; mud hsct; remission; hsct ... See more keywords
Clinical implications of SRSF2 mutations in AML patients undergoing allogeneic stem cell transplantation
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DOI: 10.1002/ajh.26298
Abstract: The SRSF2 mutations are frequently found in acute myeloid leukemia (AML) and mostly affect the P95 residue. Mutations in this splicing factor mediate abnormal splicing associated with exon skipping events, including EZH2 as a crucial… read more here.
Keywords: aml patients; hsct; clinical implications; implications srsf2 ... See more keywords
The Registry Data Analysis of HSCT on Systemic Chronic Active EBV Infection Patients in Japan.
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DOI: 10.1002/ajh.26544
Abstract: The effects of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on systemic chronic active Epstein-Barr virus infection (sCAEBV) are yet to be analyzed in a large number of patients. Using the Japanese registry database, Transplant Registry… read more here.
Keywords: hsct systemic; systemic chronic; hsct; allo hsct ... See more keywords
Cytokine release syndrome after allogeneic stem cell transplantation with posttransplant cyclophosphamide
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DOI: 10.1002/hon.2772
Abstract: Cytokine release syndrome (CRS) is a systemic inflammatory response with aberrant immune activation and immune hyperstimulation, that leads to increased cytokine levels and inflammation. CRS has been described after antibody and cellular‐based therapies. The use… read more here.
Keywords: cytokine release; crs; hsct; release syndrome ... See more keywords
Outcomes of allogeneic hematopoietic stem cell transplantation for primary hemophagocytic lymphohistiocytosis in adults
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DOI: 10.1002/hon.3014
Abstract: Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative approach for primary hemophagocytic lymphohistiocytosis (pHLH), but data on adult patients are scarce. Here we present an 8‐year experience on HSCT for adult pHLH to… read more here.
Keywords: hsct; allogeneic hematopoietic; adult; hemophagocytic lymphohistiocytosis ... See more keywords
Identification of pediatric bronchiolitis obliterans syndrome posthematopoietic stem cell transplantation; surveillance is the key
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DOI: 10.1002/ppul.25023
Abstract: Dear Editor, We read with great interest the article by Walther et al regarding long term outcomes of bronchiolitis obliterans syndrome (BOS) in children following haematopoietic stem cell transplantation (HSCT). The authors are to be… read more here.
Keywords: bos; surveillance; hsct; lung function ... See more keywords
Ruxolitinib treatment for SR-aGVHD in patients with EBV-HLH undergoing allo-HSCT
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DOI: 10.1007/s00277-019-03864-y
Abstract: Ruxolitinib is a promising option for treating steroid-refractory acute graft-versus-host disease (SR-aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this study, we describe ruxolitinib treatment for SR-aGVHD in HSCT patients with Epstein-Barr virus-associated hemophagocytic… read more here.
Keywords: agvhd; ruxolitinib; patients ebv; treatment ... See more keywords
Comparable outcomes among unmanipulated haploidentical, matched unrelated, and matched sibling donors in BU-based myeloablative hematopoietic stem cell transplantation for intermediate and adverse risk acute myeloid leukemia in complete remission: a single-center study
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DOI: 10.1007/s00277-020-04355-1
Abstract: There are a limited number of studies comparing outcomes of busulfan (BU)-based myeloablative hematopoietic stem cell transplantation using unmanipulated haploidentical donors (HIDs), HLA-matched unrelated donors (MUDs), and HLA-matched sibling related donors (MSDs) in acute myeloid… read more here.
Keywords: complete remission; risk; outcomes among; hsct ... See more keywords
Clinical utility of measuring Epstein–Barr virus-specific cell-mediated immunity after HSCT in addition to virological monitoring: results from a prospective study
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DOI: 10.1007/s00430-019-00629-2
Abstract: Lack of virus-specific cell-mediated immunity (CMI) is associated with worse viral infection outcome in hematopoietic stem cell transplantation (HSCT). We aimed to evaluate the role of immunological monitoring of Epstein–Barr virus (EBV) infection in addition… read more here.
Keywords: ebv specific; infection; hsct; cmi ... See more keywords
Factors affecting lower limb muscle strength and cardiopulmonary fitness after allogeneic hematopoietic stem cell transplantation
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DOI: 10.1007/s00520-018-4433-5
Abstract: PurposeThe aim of this study is to clarify the factors affecting physical function after allogeneic hematopoietic stem cell transplantation (HSCT).MethodsWe retrospectively analyzed 88 patients (median age, 44.5 years) who received allogeneic HSCT. Leg extension torque and… read more here.
Keywords: hsct leg; extension torque; post; hsct ... See more keywords