Low‐dose radiation‐induced demethylation of 3β‐HSD participated in the regulation of testosterone content
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4237
Abstract: The effects of low‐dose radiation (LDR, ≤0.1 Gy) on living organisms have been the hot areas of radiation biology but do not reach a definitive conclusion yet. So far, few studies have adequately accounted for… read more here.
Keywords: demethylation; testosterone; hsd; low dose ... See more keywords
Cloning and identification of a new repressor of 3,17β-Hydroxysteroid dehydrogenase of Comamonas testosteroni.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06566-9
Abstract: BACKGROUND 3,17β-hydroxysteroid dehydrogenase (3,17β-HSD) is a key enzyme in the metabolic pathway for steroid compounds catabolism in Comamonas testosteroni. Tetracycline repressor (TetR) family, repressors existing in most microorganisms, may play key roles in regulating the… read more here.
Keywords: hsd; repressor; tetr gene; comamonas testosteroni ... See more keywords
Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114083
Abstract: Methotrexate (MTX) induces the formation of reactive oxygen species (ROS) and leads to neurotoxicity. The drug also negatively impacts neurogenesis and memory. Hesperidin (Hsd) is a major flavanoid with multiple beneficial pharmacological effects such as… read more here.
Keywords: hsd; neuroprotective effects; group; stress ... See more keywords
Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.08.165
Abstract: Bufadienolides, one kind of steroids, are the major active component secreted by ear-side gland of Bufo species. Preliminary studies on high-throughput transcriptome sequencing about B. bufo gargarizans showed that the expression of 3β-Hydroxysteroid dehydrogenase (3βHSD)… read more here.
Keywords: hsd; bbg hsd; expression; bufo ... See more keywords
Distribution and localization of 3β-hydroxysteroid dehydrogenase (3β-HSD) in the brain and its regions of the catfish Heteropneustes fossilis.
Sign Up to like & getrecommendations! Published in 2017 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2016.04.031
Abstract: In vertebrates, steroids are synthesized de novo in the central and peripheral nervous system, independent of peripheral steroidogenic glands, such as the adrenal, gonads and placenta. 3β-Hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase (3β-HSD) is a key steroidogenic enzyme in… read more here.
Keywords: hsd; brain regions; hydroxysteroid dehydrogenase; brain ... See more keywords
Malathion exposure during juvenile and peripubertal periods downregulate androgen receptor and 17-ß-HSD testicular gene expression and compromised sperm quality in rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000599
Abstract: Abstract Malathion is an insecticide that is used to control arboviruses and agricultural pests. Adolescents that are exposed to this insecticide are the most vulnerable as they are in the critical period of postnatal sexual… read more here.
Keywords: hsd; expression; group; gene expression ... See more keywords
High-salt diet aggravates pyelonephritis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0285-6
Abstract: Nature reviews | Nephrology Extracellular sodium is known to modulate immune cell function but the effects of a high-salt diet (HSD) on immunity might depend on organspecific responses to high dietary salt. The kidney response… read more here.
Keywords: hsd; salt; sodium; salt diet ... See more keywords
Effect of Hesperidin against Induced Colon Cancer in Rats: Impact of Smad4 and Activin A Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition and cancer"
DOI: 10.1080/01635581.2021.1907424
Abstract: SCOPE To evaluate the chemopreventive efficacy of hesperidin (Hsd) in 1,2-dimethylhydrazine (DMH)-induced colorectal cancer (CRC) and demonstrate its role in mothers against decapentaplegic homolog 4(Smad4) and activin A signaling pathways. METHODS AND RESULTS A CRC… read more here.
Keywords: hsd; activin signaling; activin; smad4 activin ... See more keywords
A3964 Identification of chromosome 2 differentially expressed aortic genes linked to vascular inflammation using congenic rats fed a normal and high-salt diet
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548086.02252.5c
Abstract: Objectives: Chromosome 2 (Chr2) introgression from normotensive Brown Norway (BN) rats into hypertensive Dahl salt sensitive (SS) background (consomic SB2) reduced blood pressure (BP) and vascular inflammation under a normal-salt diet (NSD). BN Chr2 may… read more here.
Keywords: salt diet; hsd; vascular inflammation; rats fed ... See more keywords
miR-329– and miR-495–mediated Prr7 down-regulation is required for homeostatic synaptic depression in rat hippocampal neurons
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.1101/2022.03.08.483397
Abstract: In rat hippocampal neurons, miRNA-dependent regulation of the synaptic Prr7 protein is required for the homeostatic synaptic depression of excitatory synapses upstream of the CDK5-SPAR pathway. Homeostatic synaptic depression (HSD) in excitatory neurons is a… read more here.
Keywords: synaptic depression; hsd; rat hippocampal; regulation ... See more keywords
High dietary biotin levels affect the footpad and hock health of broiler chickens reared at different stocking densities and litter conditions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Animal Physiology and Animal Nutrition"
DOI: 10.1111/jpn.12465
Abstract: Responses to stocking density (SD), dietary biotin concentration and litter condition were evaluated on 2016 Ross 308 male broilers in the fattening period (day 22-day 42). The birds were placed in 48 pens with either… read more here.
Keywords: hsd; biotin; litter; stocking density ... See more keywords