Functional Analysis of HSD17B3-Deficient Male Mice Reveals Roles for HSD17B7 and HSD17B12 in Testosterone Biosynthesis
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DOI: 10.1210/endocr/bqaf078
Abstract: Abstract Historically, 17β-hydroxysteroid dehydrogenase type 3 (HSD17B3) was thought to be the key enzyme responsible for testicular testosterone production. In humans, loss-of-function mutations in HSD17B3 impair testosterone production during prenatal life leading to impaired development… read more here.
Keywords: mice; hydroxysteroid dehydrogenase; testosterone production; hsd17b3 ... See more keywords