Molecular Mechanism for the Allosteric Inhibition of the Human Serotonin Transporter by Antidepressant Escitalopram.
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DOI: 10.1021/acschemneuro.1c00694
Abstract: Human serotine transporter (hSERT) is one of the most influential drug targets, and its allosteric modulators (e.g., escitalopram) have emerged to be the next-generation medication for psychiatric disorders. However, the molecular mechanism underlying the allosteric… read more here.
Keywords: molecular mechanism; transporter; escitalopram; hsert ... See more keywords