Anal cancer prevention: Solving the puzzle piece by piece
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.32726
Abstract: Although the incidence of many cancers are decreasing in the United States, the incidence of anal squamous cell cancer (ASCC) increased at approximately 2.7% per year between 2001 and 2015. What is perhaps even more… read more here.
Keywords: hsil; piece; year; anal cancer ... See more keywords
Performance of an HPV 16/18 E6 oncoprotein test for detection of cervical precancer and cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32156
Abstract: HPV testing is a better alternative for cervical cancer screening, but additional procedures are required for triage of HPV positive women. HPV encoded oncoproteins E6 and E7, as the main effectors of HPV carcinogenicity represent… read more here.
Keywords: precancer; hsil; hpv; performance ... See more keywords
Molecular Insights Into the Natural History of Anal HSIL
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70397
Abstract: Anal squamous cell carcinoma is commonly associated with human papillomavirus (HPV) infection and preceded by low‐ and high‐grade anal lesions (LSIL; HSIL). We performed a molecular comparison on paired LSIL‐ and HSIL‐lesions collected in a… read more here.
Keywords: hsil; hpv type; history; lsil hsil ... See more keywords
Working to prevent anal cancer through innovation
Sign Up to like & getrecommendations! Published in 2021 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-021-02441-8
Abstract: Anal high-grade squamous intraepithelial lesions (HSIL) are the anal cancer precursor lesion and many clinicians believe that diagnosis and treatment of these lesions will prevent progression to cancer [1]. Building on the initial safety and… read more here.
Keywords: recurrence; hsil; ablation; treatment ... See more keywords
FEN1 plays a key role in the transition from HSIL to CSCC
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-15642-0
Abstract: Cervical high-grade squamous intraepithelial lesion (HSIL) is a well-recognized precursor to cervical squamous cell carcinoma (CSCC). This study aims to explore molecular mechanisms underlying this transition. The datasets of HSIL and CSCC were downloaded from… read more here.
Keywords: hsil cscc; hsil; fen1; analysis ... See more keywords
Risk of High-Grade Cervical Dysplasia in Older Patients With a Positive Human Papillomavirus Cervical Screening Test
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Lower Genital Tract Disease"
DOI: 10.1097/lgt.0000000000000861
Abstract: Introduction The Australian National Cervical Screening Program has mandated management algorithms that are uniform across all age groups, but evidence is emerging that perhaps the risk of high-grade squamous intraepithelial lesion (HSIL) may decrease in… read more here.
Keywords: risk high; age; hsil; risk ... See more keywords
p16 Expression and Biological Behavior of Flat Vulvar Low-grade Squamous Intraepithelial Lesions (LSIL)
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000364
Abstract: Flat low-grade squamous intraepithelial lesion (LSIL) of the vulva [vulvar intraepithelial neoplasia (VIN) 1, flat condyloma] is an uncommon entity with poorly understood biological behavior. We aimed to determine the risk of subsequent vulvar high-grade… read more here.
Keywords: grade squamous; hsil; vulvar; squamous intraepithelial ... See more keywords
EP1090 Use of HPV-vaccine in prevention of recurrent HSIL after LEEP in women of reproductive age
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.1132
Abstract: Introduction/Background Women who have been treated for high-grade squamous intraepithelial neoplasia (HSIL) face an elevated risk of recurrence and invasive cervical cancer. The likelihood of recurrence depends on the grade of dysplasia, the treatment used,… read more here.
Keywords: vaccination group; hsil; hpv; vaccination ... See more keywords
Abstract 5771: The vaginal microbiome as a mediator in the relationship between Black/White race and high grade cervical intraepithelial neoplasia
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5771
Abstract: The vaginal microbiome (VMB) is implicated in the development of high-grade squamous intraepithelial lesions (HSIL). The VMB is taxonomically diverse, immunomodulatory, and racially differentiated. The VMB of Black women exhibits increased microbial diversity (associated with… read more here.
Keywords: hsil; high grade; race; relationship ... See more keywords
Development of a machine learning-based model for predicting positive margins in high-grade squamous intraepithelial lesion (HSIL) treatment by Cold Knife Conization(CKC): a single-center retrospective study
Sign Up to like & getrecommendations! Published in 2024 at "BMC Women's Health"
DOI: 10.1186/s12905-024-03180-2
Abstract: Objectives This study aims to analyze factors associated with positive surgical margins following cold knife conization (CKC) in patients with cervical high-grade squamous intraepithelial lesion (HSIL) and to develop a machine-learning-based risk prediction model. Method… read more here.
Keywords: hsil; lesion; positive margins; machine learning ... See more keywords
Risk factors for ≥high-grade anal intraepithelial lesions in MSM living with HIV and the response to topical and surgical treatments.
Sign Up to like & getrecommendations! Published in 2021 at "PloS one"
DOI: 10.1371/journal.pone.0245870
Abstract: BACKGROUND The objective of this study in MSM living with HIV was to determine the incidence of HSIL and ASCC, related factors, and the response to treatment. PATIENTS AND METHODS Data were gathered in 405… read more here.
Keywords: response; msm living; hsil; hiv ... See more keywords