Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug
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DOI: 10.1016/j.celrep.2020.108639
Abstract: SUMMARY At low temperatures, protein degradation by the AAA+ HslUV protease is very slow. New crystal structures reveal that residues in the intermediate domain of the HslU6 unfoldase can plug its axial channel, blocking productive… read more here.
Keywords: aaa hsluv; hsluv protease; autoinhibitory plug; heat ... See more keywords