Three J-proteins impact Hsp104-mediated variant-specific prion elimination: a new critical role for a low-complexity domain
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DOI: 10.1007/s00294-019-01006-5
Abstract: Prions are self-propagating protein isoforms that are typically amyloid. In Saccharomyces cerevisiae , amyloid prion aggregates are fragmented by a trio involving three classes of chaperone proteins: Hsp40s, also known as J-proteins, Hsp70s, and Hsp104.… read more here.
Keywords: prion; low complexity; variant specific; hsp104 mediated ... See more keywords