Nucleotide Exchange Factors for Hsp70 Chaperones.
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DOI: 10.1007/978-1-4939-7477-1_13
Abstract: The ATPase cycle of Hsp70 chaperones controls their transient association with substrates and thus governs their function in protein folding. Nucleotide exchange factors (NEFs) accelerate ADP release from Hsp70, which results in rebinding of ATP… read more here.
Keywords: nucleotide exchange; atpase; hsp70 chaperones; exchange factors ... See more keywords
The remarkable multivalency of the Hsp70 chaperones
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DOI: 10.1007/s12192-017-0776-y
Abstract: Hsp70 proteins are key to maintaining intracellular protein homeostasis. To carry out this task, they employ a large number of cochaperones and adapter proteins. Here, we review what is known about the interaction between the… read more here.
Keywords: hsp70; remarkable multivalency; hsp70 chaperones; biology ... See more keywords
HSP70 and their co-chaperones in the human malaria parasite P. falciparum and their potential as drug targets
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DOI: 10.3389/fmolb.2022.968248
Abstract: As part of their life-cycle, malaria parasites undergo rapid cell multiplication and division, with one parasite giving rise to over 20 new parasites within the course of 48 h. To support this, the parasite has… read more here.
Keywords: parasite falciparum; chaperones human; malaria parasite; hsp70 chaperones ... See more keywords