Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins.
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DOI: 10.1021/acs.biochem.3c00531
Abstract: The 13 Hsp70 proteins in humans act on unique sets of substrates with diversity often being attributed to J-domain-containing protein (Hsp40 or JDP) cofactors. We were therefore surprised to find drastically different binding affinities for… read more here.
Keywords: hsp70 substrate; binding; binding domains; substrate binding ... See more keywords