In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors
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DOI: 10.3390/biom12070884
Abstract: Hsp90 is a promising target for the development of novel agents for cancer treatment. The N-terminal Hsp90 inhibitors have several therapeutic limitations, the most important of which is the induction of heat shock response, which… read more here.
Keywords: hsp90 ctd; structural class; hsp90; novel structural ... See more keywords