STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway
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DOI: 10.3389/fonc.2020.01102
Abstract: Oncosuppressor TP53 and oncogene STAT3 have been shown to engage an interplay in which they negatively influence each other. Conversely, mutant (mut) p53 may sustain STAT3 phosphorylation by displacing SH2 phosphatase while whether STAT3 could… read more here.
Keywords: mutp53; mevalonate pathway; stat3; hsp90 mevalonate ... See more keywords