Abstract 1033: NANOG-HSP90A axis confers immunotherapeutic resistance by blocking anti-tumor immunity cycle
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-1033
Abstract: T cell-based immunotherapy has shifted the paradigm for cancer treatment. However, the majority of patients lack effective responses due to presence of immune-refractory tumor cells that limits its clinical success by blocking amplification of anti-tumor… read more here.
Keywords: hsp90a; tumor immunity; anti tumor; immunity cycle ... See more keywords
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells
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DOI: 10.3390/ijms222313170
Abstract: (20S) ginsenoside Rh2 (G-Rh2), a major bioactive metabolite of ginseng, effectively inhibits the survival and proliferation of human liver cancer cells. However, its molecular targets and working mechanism remain largely unknown. Excitingly, we screened out… read more here.
Keywords: rh2; hsp90a; 20s rh2; liver cancer ... See more keywords