MiR-302c-5p affects the stemness and cisplatin resistance of nasopharyngeal carcinoma cells by regulating HSP90AA1
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001392
Abstract: Nasopharyngeal carcinoma (NPC) is one of the most frequent malignant tumors diagnosed in China. Cisplatin is one of the most commonly used anticancer drugs containing platinum in combined chemotherapy. The molecular mechanism of NPC is… read more here.
Keywords: hsp90aa1; mir 302c; cisplatin resistance;
Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development.
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DOI: 10.1530/rep-23-0411
Abstract: In brief: HSP90AA1 is a ubiquitous molecular chaperone that can resist cellular stress, such as oxidative stress and apoptosis, and mediate the efficacy and protein folding of normal cells during heat stress, as well as… read more here.
Keywords: inhibition hsp90aa1; maturation; embryonic development; hsp90aa1 ... See more keywords
Astragaloside IV confronts amyloid-beta-induced astrocyte senescence via hsp90aa1.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of applied biomedicine"
DOI: 10.32725/jab.2024.015
Abstract: Cell senescence is intensively related to aging and neurodegenerative diseases. This study aimed to explore the effect and targets of Astragaloside IV against amyloid-beta-induced astrocyte senescence. Oligomerized amyloid-beta was prepared to culture with human astrocytes.… read more here.
Keywords: senescence; beta; hsp90aa1; beta induced ... See more keywords
Analysis of the prognostic, diagnostic and immunological role of HSP90α in malignant tumors
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DOI: 10.3389/fonc.2022.963719
Abstract: Heat shock protein 90α (HSP90α) encoded by the HSP90AA1 gene, is the stress inducible isoform of the molecular chaperone HSP90, and was demonstrated as a promising hallmark to diagnose, prognosis in malignant tumors. This study… read more here.
Keywords: hsp90 malignant; hsp90aa1; malignant tumors; prognosis ... See more keywords
Adunctin E from Conamomum rubidum Induces Apoptosis in Lung Cancer via HSP90AA1 Modulation: A Network Pharmacology and In Vitro Study
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DOI: 10.3390/ijms252111368
Abstract: Lung cancer stands out as a leading cause of death among various cancer types, highlighting the urgent need for effective anticancer drugs and the discovery of new compounds with potent therapeutic properties. Natural sources, such… read more here.
Keywords: cancer; lung cancer; pharmacology; hsp90aa1 ... See more keywords