Articles with "hsp90n" as a keyword



Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.847556

Abstract: New targeted chemotherapy agents greatly improved five-year survival in NSCLC patients, but which were susceptible to drug resistance. NVP-AUY922, terminated in phase II clinical trials, exhibited promising anti-NSCLC (non-small-cell lung cancer) activity targeting to Hsp90N… read more here.

Keywords: hsp90n; nvp auy922; complex crystal; auy922 ... See more keywords