HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00549-23
Abstract: PEDV infection causes severe piglet mortality and threatens the global pig industry. However, the complex invasion mechanism of PEDV makes its prevention and control difficult. ABSTRACT Porcine epidemic diarrhea virus (PEDV) has caused huge economic… read more here.
Keywords: internalization; lysosomal pathway; infection; hspa5 ... See more keywords
HSPA5 Could Be a Prognostic Biomarker Correlated with Immune Infiltration in Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/7177192
Abstract: Background Breast cancer (BC) is a frequent disease in females. The heat shock 70 kDa protein 5 (HSPA5) has recently been discovered to have an important function in tumor growth. However, the biological significance of HSPA5… read more here.
Keywords: hspa5; breast cancer; immune infiltration; correlated immune ... See more keywords
New progresses on cell surface protein HSPA5/BiP/GRP78 in cancers and COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1166680
Abstract: Heat-shock-protein family A (Hsp70) member 5 (HSPA5), aliases GRP78 or BiP, is a protein encoded with 654 amino acids by the HSPA5 gene located on human chromosome 9q33.3. When the endoplasmic reticulum (ER) was stressed,… read more here.
Keywords: cell surface; hspa5; bip grp78; hspa5 bip ... See more keywords
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065144
Abstract: Heat shock protein family A (HSP70) member 5 (HSPA5) is aberrantly expressed in various tumors and closely associated with the progression and prognosis of cancer. Nevertheless, its role in bladder cancer (BCa) remains elusive. The… read more here.
Keywords: hspa5 promotes; hspa5; bladder cancer; cancer ... See more keywords
HSPA5 is a prognostic biomarker correlated with immune infiltrates in thyroid carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Endokrynologia Polska"
DOI: 10.5603/ep.a2022.0045
Abstract: INTRODUCTION Thyroid carcinoma (THCA) is the most common endocrine malignancy. Recent research has shown heat shock protein family A (HSPA5) as a diagnostic and prognostic biomarker for various malignancies. Nevertheless, the role of HSPA5 in… read more here.
Keywords: test; prognostic biomarker; hspa5; expression ... See more keywords