Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin.
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DOI: 10.1073/pnas.2213765120
Abstract: Small heat-shock proteins (sHSPs) are a widely expressed family of ATP-independent molecular chaperones that are among the first responders to cellular stress. Mechanisms by which sHSPs delay aggregation of client proteins remain undefined. sHSPs have… read more here.
Keywords: hspb4 hspb5; activity toward; crystallin; chaperone ... See more keywords