pH Effects Can Dominate Chemical Shift Perturbations in 1H,15N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00782
Abstract: 1H,15N-Heteronuclear Single Quantum Coherence (HSQC) NMR is a powerful technique that has been employed to characterize small-molecule interactions with intrinsically disordered monomeric α-Synuclein (aSyn). We report how solution pH can impact the interpretation of aSyn… read more here.
Keywords: small molecule; spectroscopy; hsqc nmr; dopa ... See more keywords
Automated analysis for multiplet identification from ultra-high resolution 2D- 1H, 13C-HSQC NMR spectra
Sign Up to like & getrecommendations! Published in 2022 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.18248.2
Abstract: Background: Metabolism is essential for cell survival and proliferation. A deep understanding of the metabolic network and its regulatory processes is often vital to understand and overcome disease. Stable isotope tracing of metabolism using nuclear… read more here.
Keywords: 13c hsqc; analysis; hsqc nmr; nmr spectra ... See more keywords
Simultaneous Synthesis of Vitamins D2, D4, D5, D6, and D7 from Commercially Available Phytosterol, β-Sitosterol, and Identification of Each Vitamin D by HSQC NMR
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DOI: 10.3390/metabo9060107
Abstract: We succeeded in simultaneously synthesizing the vitamin D family, vitamins D2, D4, D5, D6, and D7, from β-sitosterol, which is sold as a commercially available reagent from Tokyo Chemical Industry Co., Ltd. It is officially… read more here.
Keywords: vitamins commercially; synthesis vitamins; simultaneous synthesis; hsqc nmr ... See more keywords
Application of Band-Selective HSQC NMR in Species Discrimination and Adulteration Identification of Panax Linn
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DOI: 10.3390/molecules28114332
Abstract: The quality of Panax Linn products available in the market is threatened by adulteration with different Panax species, such as Panax quinquefolium (PQ), Panax ginseng (PG), and Panax notoginseng (PN). In this paper, we established… read more here.
Keywords: hsqc nmr; identification; band selective; panax ... See more keywords