Bilateral Acute Retinal Necrosis After Oncolytic HSV-1 Treatment of Glioblastoma.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2024.3772
Abstract: This case report discusses a case of bilateral acute retinal necrosis after administration of a recombinant oncolytic herpes simplex virus type 1 (HSV-1) in a 55-year-old patient with a grade IV glioblastoma. read more here.
Keywords: acute retinal; hsv; bilateral acute; necrosis oncolytic ... See more keywords
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202508464
Abstract: Incurable infection by herpes simplex virus 1 (HSV-1) can cause severe encephalitis and neurodegenerative diseases, e.g., Alzheimer's disease (AD) and amyotrophic lateral sclerosis. How HSV-1 reaches the brain from the initial infection site remains inconclusive.… read more here.
Keywords: brain; skin brain; hsv; virus ... See more keywords
Novel mutations in antiviral multiresistant HSV‐2 genital lesion: A case report
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28070
Abstract: HSV‐2 antiviral resistance mainly occurs in immunocompromised patients and especially in HIV‐positive individuals receiving long‐term antiviral treatment. Those situations can be challenging as few alternatives are available for HSV infection management. To describe clinical and… read more here.
Keywords: hsv genital; hsv; genital lesion; resistance ... See more keywords
The association between serum 25‐hydroxyvitamin D and the prevalence of herpes simplex virus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28297
Abstract: Previous studies have reported a potential anti‐infection effect for vitamin D. However, the relationship between vitamin D status and herpes simplex virus (HSV) infection has not yet been evaluated. Therefore, this study aimed to determine… read more here.
Keywords: serum; infection; hsv; hsv hsv ... See more keywords
Impact of Tobacco Use on Herpes Simplex Virus Infections: Findings From a National Survey
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70042
Abstract: Herpes simplex virus (HSV) infections, primarily caused by HSV‐1 and HSV‐2, are prevalent worldwide and carry significant health implications. The impact of tobacco use on HSV infections, however, remains underexplored. This cross‐sectional study utilized the… read more here.
Keywords: tobacco use; hsv infections; hsv; herpes simplex ... See more keywords
Unraveling the Gut‐Brain‐Immune Interplay in Herpes Simplex Virus‐Associated Neurodegeneration
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70504
Abstract: Herpes simplex virus type 1 (HSV‐1), a ubiquitous neurotropic virus, has been increasingly associated with neurodegenerative disorders through mechanisms extending beyond acute encephalitis to include chronic neuroinflammation, proteostatic disruption, and immune dysregulation. Simultaneously, the gut‐brain‐immune… read more here.
Keywords: brain; hsv; virus; gut brain ... See more keywords
Langerhans cells and sexual transmission of HIV and HSV
Sign Up to like & getrecommendations! Published in 2017 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.1923
Abstract: Langerhans cells (LCs) situated in stratified squamous epithelium of the skin and mucosal tissue are amongst the first cells that sexually transmitted pathogens encounter during transmission. They are potent antigen presenting cells and play a… read more here.
Keywords: hsv; transmission; hiv; role ... See more keywords
Expression, Purification, and Crystallization of HSV-1 Glycoproteins for Structure Determination.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_23
Abstract: Herpes simplex viruses utilize glycoproteins displayed on the viral envelope to perform a variety of functions in the viral infectious cycle. Structural and functional studies of these viral glycoproteins can benefit from biochemical, biophysical, and structural analysis of… read more here.
Keywords: purification crystallization; hsv; expression purification;
Pulmonary herpes simplex virus and cytomegalovirus in patients with acute respiratory distress syndrome related to COVID-19
Sign Up to like & getrecommendations! Published in 2024 at "Intensive Care Medicine"
DOI: 10.1007/s00134-024-07529-x
Abstract: Human herpesviruses, particularly cytomegalovirus (CMV) and herpes simplex virus (HSV), frequently reactivate in critically ill patients, including those with acute respiratory distress syndrome (ARDS) related to coronavirus disease 2019 (COVID-19). The clinical interpretation of pulmonary… read more here.
Keywords: acute respiratory; respiratory distress; hsv; herpes simplex ... See more keywords
Use of computed tomography volumetric measurements to predict operative techniques in paraesophageal hernia repair
Sign Up to like & getrecommendations! Published in 2019 at "Surgical Endoscopy"
DOI: 10.1007/s00464-019-06930-8
Abstract: Background Despite advances in diagnostic imaging capabilities, little information exists concerning the impact of physical dimensions of a paraesophageal hernia (PEH) on intraoperative decision making. The authors hypothesized that computerized volumetric analysis and multidimensional visualization… read more here.
Keywords: hsv; hda; volumetric measurements; paraesophageal hernia ... See more keywords
Tailoring acyclovir prodrugs with enhanced antiviral activity: rational design, synthesis, human plasma stability and in vitro evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2590-y
Abstract: Bile acid prodrugs have served as a viable strategy for refining the pharmaceutical profile of parent drugs through utilizing bile acid transporters. A series of three ester prodrugs of the antiherpetic drug acyclovir (ACV) with… read more here.
Keywords: acv; hsv; plasma stability; antiviral activity ... See more keywords