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   Articles with "hsv infection" as a keyword



Extracellular Vesicles Containing MDP Derived from Lactobacillus rhamnosus GG Inhibit HSV‐2 Infection by Activating the NOD2‐IFN‐I Signalling Pathway

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recommendations! Published in 2025 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.70152

Abstract: ABSTRACT The immune evasion strategies and lifelong latency of herpes simplex virus type 2 (HSV‐2) present significant challenges for effective treatment. Recent studies have demonstrated that the commensal microbiota plays an important role in regulating… read more here.

Keywords: extracellular vesicles; hsv infection; inhibit hsv; infection ... See more keywords

Microglia innate immune response contributes to the antiviral defense and blood–CSF barrier function in human choroid plexus organoids during HSV‐1 infection

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recommendations! Published in 2023 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28472

Abstract: The choroid plexus (ChP) is the source of cerebrospinal fluid (CSF). The ChP–CSF system not only provides the necessary cushion for the brain but also works as a sink for waste clearance. During sepsis, pathogens… read more here.

Keywords: csf; barrier; hsv infection; innate immune ... See more keywords

HSV‐1 infection‐induced herpetic neuralgia involves a CCL5/CCR5‐mediated inflammation mechanism

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recommendations! Published in 2023 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28718

Abstract: Herpetic‐related neuralgia (HN) caused by varicella‐zoster virus (VZV) infection is one of the most typical and common neuropathic pain in the clinic. However, the potential mechanisms and therapeutic approaches for the prevention and treatment of… read more here.

Keywords: infection induced; infection; hsv infection; spinal cord ... See more keywords
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Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea

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recommendations! Published in 2018 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-018-2938-1

Abstract: Herpes simplex virus type-1 (HSV-1) is a ubiquitous pathogen that infects a large majority of the human population worldwide. It is also a leading cause of infection-related blindness in the developed world. HSV-1 infection of… read more here.

Keywords: infection; infection cornea; hsv infection; herpes simplex ... See more keywords

Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation

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recommendations! Published in 2019 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2019.104598

Abstract: Abstract As antiviral drug resistance develops and new viruses emerge there is a pressing need to develop strategies to rapidly develop antiviral therapeutics. Here we use phospho-specific flow cytometry to assess perturbations of many different… read more here.

Keywords: ribavirin; antiviral drug; cellular signaling; drug ... See more keywords
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Matrix metalloproteinase 14 regulates HSV-1 infection in neuroblastoma cells.

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recommendations! Published in 2021 at "Antiviral research"

DOI: 10.1016/j.antiviral.2021.105116

Abstract: Growing evidence supports that chronic or latent infection of the central nervous system might be implicated in Alzheimer's disease (AD). Among them, Herpes simplex virus type 1 (HSV-1) has emerged as a major factor in… read more here.

Keywords: regulates hsv; matrix metalloproteinase; metalloproteinase regulates; infection ... See more keywords

PEDF plus DHA modulate inflammation and stimulate nerve regeneration after HSV‐1 infection

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recommendations! Published in 2017 at "Experimental Eye Research"

DOI: 10.1016/j.exer.2017.06.015

Abstract: ABSTRACT Herpes simplex virus type‐1 (HSV‐1) infection leads to impaired corneal sensation and, in severe cases, to corneal ulceration, melting and perforation. Here, we explore the potential therapeutic action of pigment epithelial‐derived factor (PEDF) plus… read more here.

Keywords: hsv infection; treatment; dha; pedf ... See more keywords
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The association between herpes simplex virus type 1 infection and Alzheimer’s disease

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recommendations! Published in 2020 at "Journal of Clinical Neuroscience"

DOI: 10.1016/j.jocn.2020.10.044

Abstract: There is growing evidence demonstrating the relationship between herpes simplex virus type 1 (HSV-1) infection and Alzheimer's disease (AD). We searched PubMed, Embase, and Cochrane databases for relevant articles. The Newcastle-Ottawa Scale (NOS) was used… read more here.

Keywords: virus type; infection; hsv infection; infection alzheimer ... See more keywords
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Herpes simplex virus and Alzheimer's disease: a Mendelian randomization study

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recommendations! Published in 2021 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2020.09.025

Abstract: This study assessed if any herpes simplex virus (HSV) infection was a genetically valid target for late-onset Alzheimer's disease (AD) using 2-sample Mendelian randomization. We applied strong (p-value read more here.

Keywords: late onset; alzheimer disease; infection; hsv infection ... See more keywords

Effect of castalagin against HSV-1 infection in newborn mice.

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recommendations! Published in 2023 at "Natural product research"

DOI: 10.1080/14786419.2023.2173191

Abstract: We tested in vivo anti-herpetic effect of castalagin, an ellagitannin compound, extracted from pedunculate oak (Quercus robur). Previous investigations found that castalagin possesses a strong inhibitory effect in vitro against HSV-1/2 equal to acyclovir (ACV). It is… read more here.

Keywords: effect; castalagin; hsv infection; effect castalagin ... See more keywords

Management of neonates born to mothers with active genital herpes simplex virus infection: an alternative approach.

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recommendations! Published in 2025 at "Current opinion in infectious diseases"

DOI: 10.1097/qco.0000000000001129

Abstract: PURPOSE OF REVIEW Although considered a rare disease, neonatal HSV infection represents a disease in urgent need of preventive strategies, as it results in substantial neonatal morbidity and mortality. This review summarizes its current epidemiology… read more here.

Keywords: hsv infection; born mothers; infection; management ... See more keywords