In utero gene editing as a treatment for heritable metabolic syndromes
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-018-0121-2
Abstract: CRISPRmediated therapeutic editing of metabolic genes. Nat. Med. 24, 1513–1518 (2018) Some heritable diseases manifest during the fetal stage, causing considerable morbidity or mortality after birth. Editing the genome and correcting these mutations in utero… read more here.
Keywords: treatment; gene editing; ht1; fah mice ... See more keywords
The northern corn leaf blight resistance gene Ht1 encodes an nucleotide-binding, leucine-rich repeat immune receptor.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular plant pathology"
DOI: 10.1111/mpp.13267
Abstract: Northern corn leaf blight, caused by the fungal pathogen Exserohilum turcicum, is a major disease of maize. The first major locus conferring resistance to E. turcicum race 0, Ht1, was identified over 50 years ago, but the… read more here.
Keywords: ph4gp ht1; northern corn; ht1; resistance ... See more keywords
Stomatal CO2/bicarbonate sensor consists of two interacting protein kinases, Raf-like HT1 and non-kinase-activity requiring MPK12/MPK4
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq6161
Abstract: The continuing rise in the atmospheric carbon dioxide (CO2) concentration causes stomatal closing, thus critically affecting transpirational water loss, photosynthesis, and plant growth. However, the primary CO2 sensor remains unknown. Here, we show that elevated… read more here.
Keywords: kinase activity; ht1; co2 bicarbonate; co2 ... See more keywords
Expression of Jerusalem artichoke (Helianthus tuberosus L.) fructosyltransferases, and high fructan accumulation in potato tubers
Sign Up to like & getrecommendations! Published in 2019 at "Applied Biological Chemistry"
DOI: 10.1186/s13765-019-0481-x
Abstract: Fructans are polymers of fructose that are present as storage carbohydrates in various plants. Jerusalem artichoke (Helianthus tuberosus L.) contains a high amount of inulin. Two enzymes are involved in inulin biosynthesis. The sucrose:sucrose 1-fructosyltransferase… read more here.
Keywords: artichoke helianthus; ht1; potato; helianthus tuberosus ... See more keywords