Activation of 5-HT1A postsynaptic receptors by NLX-101 results in functional recovery and an increase in neuroplasticity in mice with brain ischemia
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DOI: 10.1016/j.pnpbp.2019.109832
Abstract: Pharmacological interventions that selectively activate serotonin 5-hydroxytryptramine-1A (5-HT1A) heteroreceptors may prevent or attenuate the consequences of brain ischemic episodes. The present study investigated whether the preferential 5-HT1A postsynaptic receptor agonist NLX-101 (a.k.a. F15599) mitigates cognitive… read more here.
Keywords: brain ischemia; neuroplasticity mice; brain; ht1a postsynaptic ... See more keywords