Serotonin 5-HT1B receptor-mediated behavior and binding in mice with the overactive and dysregulated serotonin transporter Ala56 variant.
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DOI: 10.1007/s00213-020-05758-8
Abstract: RATIONALE Elevated whole-blood serotonin (5-HT) is a robust biomarker in ~ 30% of patients with autism spectrum disorders, in which repetitive behavior is a core symptom. Furthermore, elevated whole-blood 5-HT has also been described in patients… read more here.
Keywords: receptor; mice; serotonin transporter; ht1b receptor ... See more keywords
5-HT1B receptor agonist attenuates cocaine self-administration after protracted abstinence and relapse in rats
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DOI: 10.1177/02698811211019279
Abstract: Background: The 5-HT1B receptor (5-HT1BR) agonist, CP94253, enhances cocaine intake during maintenance of self-administration (SA) but attenuates intake after 21 days of forced abstinence in male rats. Aims: We examined whether CP94253 attenuates cocaine intake in… read more here.
Keywords: self administration; cocaine intake; relapse; abstinence ... See more keywords