P.1.006 Chronic administration of clozapine increases the level of serotonin 5-HT1A receptor heterodimerisation with 5-HT2A or D2 receptors in the mouse cortex
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DOI: 10.1016/j.euroneuro.2017.12.024
Abstract: Background and Aims It is well established that dopamine D2 receptors and serotonin 5-HT1A and 5-HT2A receptors play an important role in neurotransmission and that alterations in their functioning are implicated in many psychiatric disorders,… read more here.
Keywords: ht2a receptors; ht1a ht2a; ht1a; receptors mouse ... See more keywords
Activation of 5-HT2A Receptors Restores KCC2 Function and Reduces Neuropathic Pain after Spinal Cord Injury
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DOI: 10.1016/j.neuroscience.2017.08.033
Abstract: Downregulation of the potassium chloride cotransporter type 2 (KCC2) after a spinal cord injury (SCI) disinhibits motoneurons and dorsal horn interneurons causing spasticity and neuropathic pain, respectively. We showed recently (Bos et al., 2013) that… read more here.
Keywords: ht2a receptors; kcc2 function; neuropathic pain; injury ... See more keywords
5‑Hydroxytryptamine 2A receptor inverse agonist pimavanserin impairs maternal behavior in postpartum female rats
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DOI: 10.1016/j.pbb.2018.10.007
Abstract: ABSTRACT Maternal behavior is a highly motivated and well‐organized social behavior. Although previous studies have shown that 5‐hydroxytryptamine 2A/2C (5‐HT2A/2C) receptors play an important role in mediating the expression of normal maternal behavior, the role… read more here.
Keywords: ht2a receptors; activity ht2a; behavior; maternal behavior ... See more keywords