Orthosteric and Allosteric Activation of Human 5-HT3A Receptors.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2020.08.029
Abstract: The serotonin type 3 receptor (5-HT3) is a ligand-gated ion channel that converts the binding of the neurotransmitter serotonin (5-HT) into a transient cation current that mediates fast excitatory responses in peripheral and central nervous… read more here.
Keywords: orthosteric allosteric; human ht3a; activation; allosteric activation ... See more keywords
5‐HT3A receptors maintain hippocampal LTP in a CB1 and GABAA receptor‐ dependent manner for spatial memory
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15793
Abstract: As the only ionotropic receptor in the 5‐HT receptor family, the 5‐HT3 receptor (5‐HT3R) is involved in psychiatric disorders and its modulators have potential therapeutic effects for cognitive impairment in these disorders. However, it remains… read more here.
Keywords: hippocampal ltp; ht3a receptors; receptors maintain; memory ... See more keywords