Interaction between hippocampal serotonin and cannabinoid systems in reactivity to spatial and object novelty detection
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2016.09.059
Abstract: HighlightsActivation or blockade of 5‐HT4 receptors impaired spatial memory.CB1 receptors activation impaired spatial and novelty, while their blockade facilitated novelty.Subthreshold dose of RS67333 restored ACPA response.Subthreshold dose of RS23597 differently affect ACPA signaling.Effective dose of… read more here.
Keywords: ht4; response; novelty; spatial object ... See more keywords
Cardiovascular effects of metoclopramide and domperidone on human 5-HT4-serotonin-receptors in transgenic mice and in human atrial preparations.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174074
Abstract: It is unclear whether metoclopramide and domperidone act on human cardiac serotonin 5-HT4-receptors. Therefore, we studied transgenic mice that only express the human 5-HT4 receptor in cardiomyocytes in the atrium and in the ventricle (5-HT4-TG),… read more here.
Keywords: ht4; transgenic mice; human ht4; metoclopramide domperidone ... See more keywords
The 5-HT4 receptor-mediated inhibition of visceral nociceptive neurons in the rat caudal ventrolateral medulla
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.07.039
Abstract: Activation of the serotonin type 4 (5-HT4) receptors has been reported to improve abdominal pain in patients with functional gastrointestinal disorders and reduce visceral nociception in animal models. Earlier studies have proposed that 5-HT4 agonist… read more here.
Keywords: caudal ventrolateral; ht4 receptor; ht4; ventrolateral medulla ... See more keywords
Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
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DOI: 10.3390/ijms24054765
Abstract: Serotonin acts solely via 5-HT4-receptors to control human cardiac contractile function. The effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as well as arrhythmias, in the human heart. In addition, 5-HT4-receptors… read more here.
Keywords: ht4; ht4 receptors; cardiac roles; serotonin receptors ... See more keywords