dUMP/F-dUMP Binding to Thymidylate Synthase: Human Versus Mycobacterium tuberculosis
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DOI: 10.1021/acsomega.0c01224
Abstract: Thymidylate synthase is an enzyme that catalyzes deoxythymidine monophosphate (dTMP) synthesis from substrate deoxyuridine monophosphate (dUMP). Thymidylate synthase of Mycobacterium tuberculosis (MtbThyX) is structurally distinct from its human analogue human thymidylate synthase (hThyA), thus drawing… read more here.
Keywords: dump dump; thymidylate synthase; tuberculosis; dump ... See more keywords