A Luciferase Functional Quantitative Assay for Measuring NF-ĸB Promoter Transactivation Mediated by HTLV-1 and HTLV-2 Tax Proteins.
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DOI: 10.1007/978-1-4939-6872-5_6
Abstract: HTLV-1 and HTLV-2 viruses express Tax transactivator proteins required for viral genome transcription and capable of transforming cells in vivo and in vitro. Although Tax oncogenic potential needs to be further elucidated, it is well… read more here.
Keywords: tax; luciferase functional; promoter; htlv htlv ... See more keywords
Reflections on Some of the Exceptional Features of HTLV-1 and HTLV-1 Research: A Perspective
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DOI: 10.3389/fimmu.2022.859654
Abstract: The report is not a review or a summary. In a manner, it is a perspective but an unusual one. It looks back to the years my colleagues and I (RG) began preparing for human… read more here.
Keywords: reflections exceptional; exceptional features; research perspective; features htlv ... See more keywords
Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2
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DOI: 10.3389/fmicb.2022.1042761
Abstract: The genome of retroviruses contains two promoter elements (called long terminal repeat or LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes generally depends on the promoter located… read more here.
Keywords: transcription; hiv htlv; htlv htlv; htlv ... See more keywords
Development and Validation of Multiplex Quantitative Real-Time PCR Assays for Simultaneous Detection and Differentiation of HTLV-1 and HTLV-2, Using Different PCR Platforms and Reagent Brands
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DOI: 10.3389/fmicb.2022.831594
Abstract: Brazil currently has the highest number of individuals infected with human T-lymphotropic virus 1- and 2- (HTLV-1 and HTLV-2) globally. At present, neither molecular protocols nor commercial assays are available for HTLV-1/-2 diagnosis or validated… read more here.
Keywords: quantitative real; htlv htlv; htlv; pcr ... See more keywords
Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases
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DOI: 10.3390/life11020127
Abstract: The human T-lymphotropic viruses (HTLVs) are causative agents of severe diseases including adult T-cell leukemia. Similar to human immunodeficiency viruses (HIVs), the viral protease (PR) plays a crucial role in the viral life-cycle via the… read more here.
Keywords: htlv; characterization specificity; proteases biochemical; biochemical characterization ... See more keywords