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   Articles with "htr8 svneo" as a keyword



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Early missed abortion is associated with villous angiogenesis via the HIF-1α/VEGF signaling pathway

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recommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"

DOI: 10.1007/s00404-018-4802-9

Abstract: PurposeTo analyze the effects of the hypoxia-inducible factor 1-alpha (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway on villous angiogenesis in early missed abortion.MethodsImmunohistochemical assays were performed to detect the expression of micro-vessel density (MVD), HIF-1α,… read more here.

Keywords: hif vegf; hif; htr8 svneo; missed abortion ... See more keywords
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Astragaloside IV protects human trophoblast HTR8/SVneo cells from H2O2-Induced oxidative stress via Nrf2-Keap1-p62 feedback loop

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recommendations! Published in 2021 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2021.104621

Abstract: Abstract Preeclampsia is one of the serious complications of pregnancy and is the main cause of maternal death. Accumulation of trophoblastic reactive oxygen species (ROS) and placental dysfunction are the potential pathogenic bases of early-onset… read more here.

Keywords: svneo cells; oxidative stress; htr8 svneo; h2o2 induced ... See more keywords

Sufentanil alleviates pre-eclampsia via silencing microRNA-24-3p to target 11β-Hydroxysteroid dehydrogenase type 2

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2066753

Abstract: ABSTRACT Pre-eclampsia (PE) is a prevalent pregnancy disease characterized by insufficient trophoblast cell migration (HTR8/SVneo). Consequently, accelerating trophoblast cell proliferation might ameliorate PE. This study assessed the effects and molecular mechanisms of Sufentanil (SUF) on… read more here.

Keywords: hsd11b2; hydroxysteroid dehydrogenase; htr8 svneo; pre eclampsia ... See more keywords
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miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway

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recommendations! Published in 2022 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"

DOI: 10.2147/dmso.s385774

Abstract: Introduction Gestational diabetes mellitus (GDM) is one of the common metabolic disorders of pregnancy and results in poor pregnancy outcomes for both mother and fetus. MiR-17-5p is considered as the strongest predictor of metabolic syndrome… read more here.

Keywords: mir; txnip; txnip nlrp3; htr8 svneo ... See more keywords
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Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway

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recommendations! Published in 2020 at "Antioxidants"

DOI: 10.3390/antiox9020121

Abstract: Pregnancy complications are associated with oxidative stress induced by accumulation of trophoblastic ROS in the placenta. We employed the human trophoblast HTR8/SVneo cell line to determine the effect of curcumin pre-treatment on H2O2-induced oxidative damage… read more here.

Keywords: svneo cells; htr8 svneo; curcumin; oxidative stress ... See more keywords
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HTRA1 in Placental Cell Models: A Possible Role in Preeclampsia

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recommendations! Published in 2023 at "Current Issues in Molecular Biology"

DOI: 10.3390/cimb45050246

Abstract: The HtrA serine peptidase 1 (HTRA1) is a multidomain secretory protein with serine–protease activity involved in the regulation of many cellular processes in both physiological and pathological conditions. HTRA1 is normally expressed in the human… read more here.

Keywords: cell; role; htra1; serine protease ... See more keywords
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[Expression of lncRNA MIR210HG in preeclampsia placental tissue and its functional analysis].

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recommendations! Published in 2021 at "Zhonghua fu chan ke za zhi"

DOI: 10.3760/cma.j.cn112141-20210118-00029

Abstract: Objective: To investigate the differential expression of long non-coding RNA (lncRNA) in placental tissues of women with preeclampsia (PE) and the effect of MIR210HG on the biological function of HTR8/SVneo cells. Methods: A total of… read more here.

Keywords: analysis; group; svneo cells; expression ... See more keywords

CTRP9 decreases high glucose-induced trophoblast cell damage by reducing endoplasmic reticulum stress

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recommendations! Published in 2022 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2022.12701

Abstract: C1q/TNF-α-related protein 9 (CTRP9) is downregulated in gestational diabetes mellitus (GDM) and may exert a protective effect against GDM, although its mechanism of action is yet to be elucidated. To investigate the specific role of… read more here.

Keywords: trophoblast cell; stress; ctrp9; htr8 svneo ... See more keywords