The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms
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DOI: 10.1038/s41598-020-80233-0
Abstract: Streptococcus pneumoniae (the pneumococcus) colonizes the human nasopharynx by forming multicellular biofilms. Due to the high level of asymptomatic carriage, transition to infections, such as otitis media, pneumonia, sepsis, and meningitis, occurs often enough that… read more here.
Keywords: biofilm dispersal; protease; heat induced; pneumococcal biofilms ... See more keywords
Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA
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DOI: 10.1080/19490976.2020.1810532
Abstract: ABSTRACT Campylobacter jejuni is a predominant zoonotic pathogen causing gastroenteritis and other diseases in humans. An important bacterial virulence factor is the secreted serine protease HtrA (HtrA Cj ), which targets tight and adherens junctional… read more here.
Keywords: campylobacter jejuni; protease; microscopy; serine protease ... See more keywords
E-Cadherin Orthologues as Substrates for the Serine Protease High Temperature Requirement A (HtrA)
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DOI: 10.3390/biom12030356
Abstract: Helicobacter pylori (H. pylori) expresses the serine protease and chaperone High temperature requirement A (HtrA) that is involved in periplasmic unfolded protein stress response. Additionally, H. pylori-secreted HtrA directly cleaves the human cell adhesion molecule… read more here.
Keywords: temperature requirement; cadherin orthologues; serine protease; htra ... See more keywords
Campylobacter jejuni Serine Protease HtrA Induces Paracellular Transmigration of Microbiota across Polarized Intestinal Epithelial Cells
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DOI: 10.3390/biom12040521
Abstract: Campylobacter jejuni represents an eminent zoonotic germ responsible for foodborne infections causing campylobacteriosis. In addition, infections with C. jejuni constitute a risk factor for the occurrence of inflammatory bowel disease (IBD). In the latter case,… read more here.
Keywords: transmigration microbiota; microbiota; campylobacter jejuni; htra ... See more keywords