HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.
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DOI: 10.1021/acsmedchemlett.7b00483
Abstract: We have recently proposed a novel drug discovery approach based on biophysical screening of focused positional scanning libraries in which each element of the library contained a common binding moiety for the given target or… read more here.
Keywords: potent selective; nmr identification; hts nmr; selective inhibitors ... See more keywords